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Epidemiology and Biostatistics

An Introduction to Clinical Research

  • Textbook
  • © 2019

Overview

Authors:
  1. Bryan Kestenbaum

    1. Division of Nephrology, Department of Medicine, University of Washington, Seattle, USA

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  • Compact and comprehensive – perfect length and coverage for medical school courses
  • Basic concepts of epidemiology and of biostatistics presented and illustrated with extensive examples from the clinical literature
  • Learning objectives frame beginning of each chapter
  • New – chapter on genetic epidemiology
  • New – updated coverage of effect modification, diagnostic testing, and randomized trials

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Table of contents (18 chapters)

  1. Front Matter

    Pages i-xiv
    Download chapter PDF

  2. Epidemiology

    1. Front Matter

      Pages 1-1
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    2. Causal Relationships in Health and Disease

      • Bryan Kestenbaum
      Pages 3-10

    3. Basic Measures of Disease Frequency

      • Bryan Kestenbaum
      Pages 11-20

    4. General Considerations in Epidemiologic Research

      • Bryan Kestenbaum
      Pages 21-34

    5. Case Reports and Case Series

      • Bryan Kestenbaum
      Pages 35-38

    6. Cross-Sectional Studies

      • Bryan Kestenbaum
      Pages 39-43

    7. Cohort Studies

      • Bryan Kestenbaum
      Pages 45-61

    8. Case-Control Studies

      • Bryan Kestenbaum
      Pages 63-78

    9. Randomized Trials

      • Bryan Kestenbaum
      Pages 79-111

    10. Misclassification

      • Bryan Kestenbaum
      Pages 113-124

    11. Confounding

      • Bryan Kestenbaum
      Pages 125-142

    12. Effect Modification

      • Bryan Kestenbaum
      Pages 143-155

    13. Screening and Diagnosis

      • Bryan Kestenbaum
      Pages 157-183

  3. Biostatistics

    1. Front Matter

      Pages 185-185
      Download chapter PDF

    2. Summary Measures in Statistics

      • Bryan Kestenbaum
      Pages 187-196

    3. Introduction to Statistical Inference

      • Bryan Kestenbaum
      Pages 197-206

    4. Hypothesis Tests in Practice

      • Bryan Kestenbaum
      Pages 207-216

    5. Linear Regression

      • Bryan Kestenbaum
      Pages 217-237

    6. Log-Link and Logistic Regression

      • Bryan Kestenbaum
      Pages 239-246
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Keywords

About this book

This is a concise introduction to epidemiology and biostatistics written specifically for medical students and first-time learners of clinical research methods.  It presents the core concepts of epidemiology and of biostatistics and illustrates them with extensive examples from the clinical literature.  It is the only book on the market written to speak directly to medical students and first-time biomedical researchers by using language and examples that are easy to understand. 

This newly updated second edition is extensively rewritten to provide the clearest explanations and examples. There is also a sister-text, a 150-problem workbook of practice problems that can be purchased alongside this textbook.  The author continues to provide a text that is attractively fast-paced and concise for use in condensed courses, such as those taught in medical school. 

The book is an excellent review for the epidemiology section of the United States Medical Licensing Examination Part I which all medical students must take at the end of the second year.

Authors and Affiliations

  • Division of Nephrology, Department of Medicine, University of Washington, Seattle, USA

    Bryan Kestenbaum

About the author

Dr. Kestenbaum is Associate Professor of Medicine at the University of Washington School of Medicine in Seattle.  He has advanced training in epidemiology and extensive experience in conducting clinical research.  A long-time teacher of the required medical school course in epidemiology and biostatistics, he began writing the First Edition out of frustration with the appropriateness for medical students of the available books which are aimed more at graduate students taking a one- or two-semester course.

Bibliographic Information

  • Book Title: Epidemiology and Biostatistics

  • Book Subtitle: An Introduction to Clinical Research

  • Authors: Bryan Kestenbaum

  • DOI: https://doi.org/10.1007/978-3-319-96644-1

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Switzerland AG 2019

  • Softcover ISBN: 978-3-319-96642-7Published: 23 October 2018

  • eBook ISBN: 978-3-319-96644-1Published: 12 October 2018

  • Edition Number: 2

  • Number of Pages: XIV, 277

  • Number of Illustrations: 59 b/w illustrations, 12 illustrations in colour

  • Topics: Epidemiology, Biostatistics

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