Advances in Experimental Medicine and Biology

Molecular, Cellular, and Tissue Engineering of the Vascular System

Editors: Fu, Bingmei, Wright, Neil (Eds.)

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  • Reviews the latest literature in vascular systems from a view of biomedical engineers
  • Covers the state-of-the-art research in endothelial surface glycocalyx, in nuclear envelope proteins, and in smooth muscle cell and surrounding extracellular matrix in maintaining vascular functions, in vulnerable plaque and abdominal aortic aneurysm, in transport across the blood-brain barrier, and in vascular system in response to temperature changes
  • Presents mathematical models for blood cell movement and interactions between circulating cells and endothelial cells forming the microvessel wall
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eBook $139.00
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  • ISBN 978-3-319-96445-4
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  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-3-319-96444-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book introduces the latest research in molecular, cellular, and tissue engineering of the vascular system. Topics covered include the roles of endothelial surface glycocalyx as a mechano-sensor and transducer for blood flow, a barrier to water and solute transport across the vascular wall and to the interaction between circulating cells and the vessel wall, the roles of nuclear envelope proteins and nuclear lamina in regulating vascular functions under blood flow-induced forces, and the roles of smooth muscle cells and extracellular components in arterial vasoconstriction. Other topics covered include non-surgical vascular interventions for coronary artery diseases, genesis and mechanisms of atherosclerotic plaque microcalcifications and human abdominal aortic aneurysms, experiments and modelling for red blood cell and tumor cell movement in microcirculation, transport across the blood-brain barrier and its role in Alzheimer’s disease, mathematical models for cell survival after hyperthermia, application of hypothermia in enhancing treatment for brain and spinal cord injuries, and damage of eardrums due to blast waves. This is an ideal book for biomedical engineers and researchers, medical researchers, and students in biomedical engineering and medical sciences.

About the authors

Bingmei M Fu is a Professor of Biomedical Engineering at The City College of the City University of New York. She received her BS and MS in Modern Mechanics from the University of Science and Technology of China, her Ph.D. in Mechanical Engineering from the City University of New York and her postdoctoral training in School of Medicine at the University of California, Davis. Prior to her appointment at City College, she was an Associate Professor in Mechanical Engineering at the University of Nevada, Las Vegas. She is a fellow of the American Institute for Medical and Biological Engineering and a member of the Biomedical Engineering Society and the American Association for the Advancement of Science. Her major research activities involve modelling nano and micro transport phenomena in the microcirculation, and corresponding in vivo animal and in vitro culture cell experiments.

Neil T. Wright is an Associate Professor of Mechanical Engineering at Michigan State University. He received his BS in Engineering Science and Mechanics from Virginia Tech, his MS in Mechanical Engineering from the University of Colorado, and his PhD in Mechanical Engineering and Applied Mechanics from the University of Pennsylvania. Prior to his appointment at Michigan State, he was an Associate Professor at the University of Maryland, Baltimore County. He is a fellow of the American Society of Mechanical Engineers and a member of the Biomedical Engineering Society and the American Association for the Advancement of Science. His laboratory measures the thermophysical properties of biological materials and superconducting niobium.

Table of contents (17 chapters)

Table of contents (17 chapters)
  • The Role of Endothelial Surface Glycocalyx in Mechanosensing and Transduction

    Zeng, Ye (et al.)

    Pages 1-27

  • The Molecular Structure of the Endothelial Glycocalyx Layer (EGL) and Surface Layers (ESL) Modulation of Transvascular Exchange

    Curry, Fitz-Roy E.

    Pages 29-49

  • Role of the Glycocalyx as a Barrier to Leukocyte-Endothelium Adhesion

    Lipowsky, Herbert H.

    Pages 51-68

  • Mechanobiology and Vascular Remodeling: From Membrane to Nucleus

    Qi, Ying-Xin (et al.)

    Pages 69-82

  • Endothelial Nuclear Lamina in Mechanotransduction Under Shear Stress

    Ji, Julie Y.

    Pages 83-104

Buy this book

eBook $139.00
price for USA in USD (gross)
  • ISBN 978-3-319-96445-4
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-3-319-96444-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Molecular, Cellular, and Tissue Engineering of the Vascular System
Editors
  • Bingmei Fu
  • Neil Wright
Series Title
Advances in Experimental Medicine and Biology
Series Volume
1097
Copyright
2018
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing AG, part of Springer Nature
eBook ISBN
978-3-319-96445-4
DOI
10.1007/978-3-319-96445-4
Hardcover ISBN
978-3-319-96444-7
Series ISSN
0065-2598
Edition Number
1
Number of Pages
VIII, 334
Number of Illustrations
19 b/w illustrations, 65 illustrations in colour
Topics