Nontuberculous Mycobacterial Disease

1. Front Matter

   Pages i-xi

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2. Nontuberculous Mycobacterial Disease: An Introduction and Historical Perspective

   • David E. Griffith

   Pages 1-14

3. Laboratory Diagnosis and Antimicrobial Susceptibility Testing of Nontuberculous Mycobacteria

   • Barbara A. Brown-Elliott

   Pages 15-59

4. Drug Susceptibility Testing of Nontuberculous Mycobacteria

   • Jakko van Ingen

   Pages 61-88

5. Vulnerability to Nontuberculous Mycobacterial Lung Disease or Systemic Infection Due to Genetic/Heritable Disorders

   • Edward D. Chan

   Pages 89-110

6. Immune Dysfunction and Nontuberculous Mycobacterial Disease

   • Emily Henkle, Kevin L. Winthrop

   Pages 111-130

7. Environmental Niches for NTM and Their Impact on NTM Disease

   • Leah Lande

   Pages 131-144

8. Epidemiology of Nontuberculous Mycobacterial Pulmonary Disease (NTM PD) in the USA

   • Shelby Daniel-Wayman, Jennifer Adjemian, D. Rebecca Prevots

   Pages 145-161

9. Global Epidemiology of NTM Disease (Except Northern America)

   • Dirk Wagner, Marc Lipman, Samantha Cooray, Felix C. Ringshausen, Kozo Morimoto, Won-Jung Koh et al.

   Pages 163-260

10. Diagnosis of NTM Disease: Pulmonary and Extrapulmonary

    • Jeremy M. Clain, Timothy R. Aksamit

    Pages 261-270

11. Nontuberculous Mycobacterial Disease Management Principles

    • Timothy R. Aksamit, David E. Griffith

    Pages 271-299

12. Mycobacterium avium Complex Disease

    • Michael R. Holt, Charles L. Daley

    Pages 301-323

13. NTM Disease Caused by M. kansasii, M. xenopi, M. malmoense, and Other Slowly Growing NTM

    • Theodore K. Marras, Sarah K. Brode

    Pages 325-368

14. Disease Caused by Mycobacterium Abscessus and Other Rapidly Growing Mycobacteria (RGM)

    • Julie V. Philley, David E. Griffith

    Pages 369-399

15. Management of Lung Diseases Associated with NTM Infection

    • Anne E. O’Donnell

    Pages 401-411

16. Surgical Management of NTM Diseases

    • James A. Caccitolo

    Pages 413-437

17. Nontuberculous Mycobacterial Disease in Pediatric Populations

    • Andrea T. Cruz, Jeffrey R. Starke

    Pages 439-463

18. Non-tuberculous Mycobacteria in Cystic Fibrosis

    • Robert Burkes, Peadar G. Noone

    Pages 465-481

19. Healthcare-Associated Outbreaks and Pseudo-Outbreaks of Nontuberculous Mycobacteria

    • Barbara A. Brown-Elliott, Richard J. Wallace Jr.

    Pages 483-503

20. Back Matter

    Pages 505-515

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This book is a comprehensive and authoritative source on nontuberculous mycobacterial (NTM) pathogens and diseases and their appropriate management, with a focus on lung disease. NTM diseases, especially lung diseases, are increasing in prevalence in the U.S. and internationally with concomitant growing interest in a broad section of the medical community. Often merely included in coverage of tuberculosis, many aspects of NTM organisms and diseases are actually very different than TB.  These differences are not intuitive or trivial and frequently result in suboptimal management of NTM patients.  This book addresses these gaps in the literature with chapters on microbiology, pathophysiology, epidemiology, the various diseases that can stem from NTM, and their particular management. There is also coverage on prevention and NTM as a public health problem. For pulmonologists and infectious disease physicians, this is the definitive resource on nontuberculous mycobacteria.

• Nontuberculous mycobacteria
• Mycobacterium avium complex
• Mycobacterium abscessus
• Nontuberculous mycobacterial disease
• infectious disease
• pulmonology
• infectious diseases

• Professor of Medicine, University of Texas Health Science Center, Tyler, USA

  David E. Griffith

Dr. Griffith is a Professor of Medicine and Pulmonary Infectious Disease Section Chief in the Department of Medicine at the University of Texas Health Science Center, Tyler.  Dr. Griffith is the Assistant Medical Director for the Heartland National Tuberculosis Center, funded by the Centers for Disease Control and Prevention (CDC). He is also the UT TB Program Director for the Texas Center for Infectious Disease (TCID) in San Antonio.  He has authored or coauthored more than 200 publications (original research papers, reviews, book chapters, editorials) related primarily to nontuberculous mycobacterial diseases.  He also participated in writing the 1997 American Thoracic Society (ATS) Statement on the Diagnosis and Treatment of Nontuberculous Mycobacterial Diseases and was chairman of the writing committee for the 2007 edition. 

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