Precision Molecular Pathology of Neoplastic Pediatric Diseases

1. Front Matter

   Pages i-viii

   PDF

2. Molecular Pathology of Pediatric Neoplasms: General Principles

   1. Front Matter

      Pages 1-1

      PDF

   2. Principles of Molecular Biology and Oncogenesis

      • Rachel L. Stewart, Selene C. Koo, Larissa V. Furtado

      Pages 3-8

   3. Molecular Methods in Oncology: Targeted Mutational Analysis

      • Jason A. Jarzembowski

      Pages 9-31

   4. Molecular Methods in Oncology: Genomic Analysis

      • Jason A. Jarzembowski

      Pages 33-44

   5. Molecular Testing in Pediatric Oncology Practice

      • Jeremy P. Segal, Lauren Ritterhouse

      Pages 45-65

   6. Molecular Targeted Therapy of Pediatric Neoplasms

      • Elizabeth A. Sokol, Navin R. Pinto

      Pages 67-86

3. Molecular Pathology of Specific Pediatric Neoplasms

   1. Front Matter

      Pages 87-87

      PDF

   2. Hematolymphoid System

      • John Choi, Jeffery M. Klco, Kamran Mirza

      Pages 89-136

   3. Pediatric Brain Tumors

      • Peter Pytel, Carrie Fitzpatrick

      Pages 137-149

   4. Neuroblastoma and Neuroblastic Tumors

      • Hiroyuki Shimada, Naohiko Ikegaki

      Pages 151-168

   5. Soft Tissue and Bone Neoplasms

      • Peter Pytel, Nicole A. Cipriani

      Pages 169-193

   6. Skin, Melanocytic Neoplasms

      • Kristen M. Paral, Thomas Krausz

      Pages 195-202

   7. Salivary Gland, Thyroid, and Parathyroid Neoplasms: Molecular Features

      • M. John Hicks

      Pages 203-238

   8. Cardiovascular and Respiratory Systems

      • Bahig M. Shehata, Nasim Khoshnam, Aliya N. Husain

      Pages 239-250

   9. Gastrointestinal Tract

      • Bruce R. Pawel

      Pages 251-279

   10. Liver and Pancreas

       • Sarangarajan Ranganathan

       Pages 281-329

   11. Molecular Pathology of Pediatric Renal Tumors

       • Selene C. Koo, Elizabeth J. Perlman

       Pages 331-349

4. Back Matter

   Pages 351-360

   PDF

This book provides a comprehensive, state-of-the art review of pediatric oncology. The text covers relevant concepts in molecular biology and addresses technical principles, applications, challenges, and integration of current and emerging genomic and molecular methods in the diagnosis and personalized management of childhood cancers. The text also discusses a wide array of pediatric neoplasms in the context of molecular pathology in a concise and understandable manner, with focus on their molecular pathogenesis, clinicopathological features, classification, molecular diagnosis, and approaches to personalized care.


Written by experts in the field, Precision Molecular Pathology of Neoplastic Pediatric Diseases serves as a valuable resource for pathologists, pediatric oncologists, trainees and researchers with an interest in pediatric and molecular pathology.
 

• Oncogenes
• FISH
• chromosomal microarray
• pleomorphic xanthoastrocytoma
• nodular fasciitis
• Cronkhite-Canada syndrome

• Department of Pathology, University of Utah/ARUP Laboratories, Salt Lake City, USA

  Larissa V. Furtado

• Department of Pathology, University of Chicago, Chicago, USA

  Aliya N. Husain

Larissa V. Furtado, MD
Medical Director, Molecular Oncology
ARUP Laboratories
Assistant Professor of Pathology
University of Utah School of Medicine
500 Chipeta Way
MS J15-113
Salt Lake City, Utah, 84108


Aliya N. Husain, MD
Professor of Pathology
University of Chicago Medicine
5841 S. Maryland Ave., Room S-627, MC 6101
Chicago, IL 60637 

Policies and ethics