Advances in Experimental Medicine and Biology

Stromal Immunology

Editors: Owens, Benjamin M.J, Lakins, Matthew (Eds.)

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  • Discusses the newfound role of stromal cells in immune response 
    Provides a solid grounding in the fundamentals of stromal immunology 
    First comprehensive resource about stromal immunology

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eBook $109.00
price for USA in USD (gross)
  • ISBN 978-3-319-78127-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $149.99
price for USA in USD
  • ISBN 978-3-319-78125-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Research into and interest in the role of stromal cells in immunology has exploded over the past 15 years. The conventional view that placed non-hematopoietic stromal cells as passive, structural, and supportive entities has now been replaced with an appreciation that these cells have active, dynamic roles during immune responses, and thus impact on the pathophysiology of multiple immune-mediated diseases. This book serves to provide solid grounding in the fundamentals of stromal immunology, focusing on the biological aspects of their function in addition to highlighting key areas for the development of the field in the future. The book is also a unique source of information on emerging concepts that place stromal cells from outside lymphoid organs as major contributors to the biology of diverse conditions, such as rheumatoid arthritis, chronic parasitic infection, inflammatory bowel disease, and cancer.

About the authors

Dr. Benjamin Owens is Head of Business Development at EUSA Pharma and an RF Lecturer in Medicine at Somerville College, University of Oxford. His prior academic research programmes focused on the role of intestinal stromal cells in human chronic intestinal inflammation. In addition to his role in Industry, he teaches stromal immunology to final year medical students.
Dr. Matthew Lakins is a Senior Scientist at F-star Biotechnology Ltd. in Cambridge, UK. Prior to this he was an MRC Career Development Fellow at the MRC Cancer Unit at the University of Cambridge. Here his research interests lay at the interface of tumor-associated stromal biology and immunology, ultimately working toward understanding and exploiting the ability of the tumor microenvironment to manipulate host tumor immunogenicity.

Together, Dr. Owens and Dr. Lakins founded the BSI Stromal Immunology affinity group in 2010 and have since organized two international meetings in York  and Cambridge.

Table of contents (8 chapters)

Table of contents (8 chapters)
  • Leukocyte-Stromal Interactions Within Lymph Nodes

    D’Rozario, Joshua (et al.)

    Pages 1-22

  • Stromal Cell Responses in Infection

    Kaye, Paul M.

    Pages 23-36

  • Fibroblasts and Osteoblasts in Inflammation and Bone Damage

    Turner, Jason D. (et al.)

    Pages 37-54

  • Molecular and Cellular Requirements for the Assembly of Tertiary Lymphoid Structures

    Mueller, C. G. (et al.)

    Pages 55-72

  • Mesenchymal Stem Cells as Endogenous Regulators of Inflammation

    Munir, Hafsa (et al.)

    Pages 73-98

Buy this book

eBook $109.00
price for USA in USD (gross)
  • ISBN 978-3-319-78127-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $149.99
price for USA in USD
  • ISBN 978-3-319-78125-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Stromal Immunology
Editors
  • Benjamin M.J Owens
  • Matthew Lakins
Series Title
Advances in Experimental Medicine and Biology
Series Volume
1060
Copyright
2018
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing AG, part of Springer Nature
eBook ISBN
978-3-319-78127-3
DOI
10.1007/978-3-319-78127-3
Hardcover ISBN
978-3-319-78125-9
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XIII, 151
Number of Illustrations
15 illustrations in colour
Topics