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Acute Neuronal Injury

The Role of Excitotoxic Programmed Cell Death Mechanisms

Editors: Fujikawa, Denson G. (Ed.)

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  • Covers major causes of nerve cell death including strokes, seizures, etc
  • Material from previous edition has been comprehensively updates
  • Includes 3 new chapters
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eBook $129.00
price for USA in USD (gross)
  • ISBN 978-3-319-77495-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
  • ISBN 978-3-319-77494-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

An overview of the biochemical mechanisms that produce acute nerve cell death in the brain. Covers injuries and disorders including stroke, brain and spinal cord trauma, hypoglycemic coma, and prolonged epileptic seizures. All of these lead to high concentrations of calcium in nerve cells which, in turn, causes degradation of cytoplasmic proteins, cleavage of nuclear DNA, and eventually cell death. 
The Second Edition contains 11 thoroughly updated chapters and 3 additional chapters that did not appear in the previous edition.

About the authors

Dr. Denson Fujikawa is an Adjunct Professor of Neurology at the David Geffen School of Medicine at UCLA, a member of the Brain Research Institute at UCLA and a Staff Neurologist at the Department of Veterans Affairs Greater Los Angeles Healthcare System. His interest in mechanisms of nerve cell death in the brain began during a two-year epilepsy research fellowship with Dr. Claude Wasterlain, from 1981 to 1983. He is a Fellow of the American Academy of Neurology and is a member of the American Epilepsy Society, American Neurological Association, International Society for Cerebral Blood Flow and Metabolism and the Society for Neuroscience.

Table of contents (11 chapters)

Table of contents (11 chapters)
  • Excitotoxic Programmed Cell Death Involves Caspase-Independent Mechanisms

    Pages 3-17

    Dawson, Ted M. (et al.)

  • To Survive or to Die: How Neurons Deal with it

    Pages 19-35

    Wang, Yubin (et al.)

  • Oxidative Damage Mechanisms in Traumatic Brain Injury and Antioxidant Neuroprotective Approaches

    Pages 39-61

    Hall, Edward D. (et al.)

  • Mitochondrial Damage in Traumatic CNS Injury

    Pages 63-81

    Hubbard, W. Brad (et al.)

  • Neuroprotective Agents Target Molecular Mechanisms of Programmed Cell Death After Traumatic Brain Injury

    Pages 83-99

    Tao, Lu-Yang

Buy this book

eBook $129.00
price for USA in USD (gross)
  • ISBN 978-3-319-77495-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
  • ISBN 978-3-319-77494-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Acute Neuronal Injury
Book Subtitle
The Role of Excitotoxic Programmed Cell Death Mechanisms
Editors
  • Denson G. Fujikawa
Copyright
2018
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing AG, part of Springer Nature
eBook ISBN
978-3-319-77495-4
DOI
10.1007/978-3-319-77495-4
Hardcover ISBN
978-3-319-77494-7
Edition Number
2
Number of Pages
XII, 215
Number of Illustrations
15 b/w illustrations, 24 illustrations in colour
Topics