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Resistance to Targeted Anti-Cancer Therapeutics

Resistance of Targeted Therapies Excluding Antibodies for Lymphomas

Editors: Ferreri, Andrés J. M (Ed.)

  • This book will focus on recently developed targeted therapies other than monoclonal antibodies used in lymphoma patients, both in routine practice and investigative trials
  • Divided by groups of drugs, the book will revisit the most relevant aspects of these targeted therapies with special emphasis on molecular mechanisms and clinical effects of resistance
  • The book features a diverse array of internationally recognized experts
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eBook $109.00
price for USA in USD (gross)
  • ISBN 978-3-319-75184-9
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $149.99
price for USA in USD
  • ISBN 978-3-319-75183-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

In the last decade, the literature on molecular mechanisms and activated pathways in the different lymphoma categories increased exponentially, which was followed by a more diffuse and successful use of targeted therapies. In this book, expert authors revisit the most relevant aspects of these therapies, with special emphasis on molecular mechanisms and clinical effects of resistance. The knowledge of the underlying mechanisms involved in tumor resistance to target therapies is of paramount importance because they will result in a better selection of patients with sensitive disease and the establishment of suitable combinations of drugs that target different molecules and could overcome the established resistance.

About the authors

Andrés J. M. Ferreri has a degree in Medicine from the Facultad de Medicina of the Universidad de Buenos Aires, Argentina (1985), and obtained the degree of Doctor in Medicine and Surgery in the Facoltà di Medicina e Chirurgia dell’Università degli Studi di Parma, Italy, in 1992. He is a Specialist in Clinical Oncology (Università degli Studi di Milan, Italy, 2005). He was a research fellow at the Divisione di Oncologia Sperimentale “E” and at the Divisione di Oncologia Médica “A” of the Istituto Nazionale dei Tumori of Milan (1989–1994) and vice-director of the Medical Oncology Unit of the San Raffaele Scientific Institute of Milan, Italy. Currently, Dr. Ferreri is Head of the Unit of Lymphoid Malignancies of the San Raffaele Scientific Institute of Milan, and is a Contract Professor of Oncology in the Vita e Salute University, Milan. He is fully devoted to the research on non-Hodgkin lymphomas and is an opinion leader in the field of extranodal lymphomas. Dr. Ferreri is Associate Editor of the ESO/START Project and of “Haematological Oncology” and Faculty of the European School of Oncology. Dr. Ferreri is a member of EHA, ESMO, ASH, and ASCO.

Table of contents (6 chapters)

  • BTK Inhibitors: Focus on Ibrutinib and Similar Agents

    Mattsson, Mattias (et al.)

    Pages 1-22

  • BCL2 Inhibitors: Insights into Resistance

    Anderson, Mary Ann (et al.)

    Pages 23-43

  • Proteasome Inhibitors with a Focus on Bortezomib

    Barley, Kevin (et al.)

    Pages 45-71

  • IMiD: Immunomodulatory Drug Lenalidomide (CC-5013; Revlimid) in the Treatment of Lymphoma: Insights into Clinical Use and Molecular Mechanisms

    Kasi, Pashtoon Murtaza (et al.)

    Pages 73-83

  • mTOR Inhibitors, with Special Focus on Temsirolimus and Similar Agents

    Calimeri, Teresa (et al.)

    Pages 85-105

Buy this book

eBook $109.00
price for USA in USD (gross)
  • ISBN 978-3-319-75184-9
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $149.99
price for USA in USD
  • ISBN 978-3-319-75183-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Resistance of Targeted Therapies Excluding Antibodies for Lymphomas
Editors
  • Andrés J. M Ferreri
Series Title
Resistance to Targeted Anti-Cancer Therapeutics
Series Volume
17
Copyright
2018
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing AG, part of Springer Nature
eBook ISBN
978-3-319-75184-9
DOI
10.1007/978-3-319-75184-9
Hardcover ISBN
978-3-319-75183-2
Series ISSN
2196-5501
Edition Number
1
Number of Pages
XIII, 138
Number of Illustrations and Tables
1 b/w illustrations, 13 illustrations in colour
Topics