Skip to main content
  • Book
  • © 2018

Resistance of Targeted Therapies Excluding Antibodies for Lymphomas

  • This book will focus on recently developed targeted therapies other than monoclonal antibodies used in lymphoma patients, both in routine practice and investigative trials
  • Divided by groups of drugs, the book will revisit the most relevant aspects of these targeted therapies with special emphasis on molecular mechanisms and clinical effects of resistance
  • The book features a diverse array of internationally recognized experts

Part of the book series: Resistance to Targeted Anti-Cancer Therapeutics (RTACT, volume 17)

Buy it now

Buying options

eBook USD 99.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 129.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

This is a preview of subscription content, log in via an institution to check for access.

Table of contents (6 chapters)

  1. Front Matter

    Pages i-xiii
  2. BTK Inhibitors: Focus on Ibrutinib and Similar Agents

    • Mattias Mattsson, Lydia Scarfò
    Pages 1-22
  3. BCL2 Inhibitors: Insights into Resistance

    • Mary Ann Anderson, Andrew W. Roberts, John F. Seymour
    Pages 23-43
  4. Proteasome Inhibitors with a Focus on Bortezomib

    • Kevin Barley, Samir Parekh
    Pages 45-71
  5. mTOR Inhibitors, with Special Focus on Temsirolimus and Similar Agents

    • Teresa Calimeri, Andrés J. M. Ferreri
    Pages 85-105
  6. Back Matter

    Pages 135-138

About this book

In the last decade, the literature on molecular mechanisms and activated pathways in the different lymphoma categories increased exponentially, which was followed by a more diffuse and successful use of targeted therapies. In this book, expert authors revisit the most relevant aspects of these therapies, with special emphasis on molecular mechanisms and clinical effects of resistance. The knowledge of the underlying mechanisms involved in tumor resistance to target therapies is of paramount importance because they will result in a better selection of patients with sensitive disease and the establishment of suitable combinations of drugs that target different molecules and could overcome the established resistance.

Editors and Affiliations

  • Department of Onco-Hematology, Unit of Lymphoid Malignancies, IRCCS San Raffaele Scientific Institute, Milan, Italy

    Andrés J. M. Ferreri

About the editor

Andrés J. M. Ferreri has a degree in Medicine from the Facultad de Medicina of the Universidad de Buenos Aires, Argentina (1985), and obtained the degree of Doctor in Medicine and Surgery in the Facoltà di Medicina e Chirurgia dell’Università degli Studi di Parma, Italy, in 1992. He is a Specialist in Clinical Oncology (Università degli Studi di Milan, Italy, 2005). He was a research fellow at the Divisione di Oncologia Sperimentale “E” and at the Divisione di Oncologia Médica “A” of the Istituto Nazionale dei Tumori of Milan (1989–1994) and vice-director of the Medical Oncology Unit of the San Raffaele Scientific Institute of Milan, Italy. Currently, Dr. Ferreri is Head of the Unit of Lymphoid Malignancies of the San Raffaele Scientific Institute of Milan, and is a Contract Professor of Oncology in the Vita e Salute University, Milan. He is fully devoted to the research on non-Hodgkin lymphomas and is an opinion leader in the field of extranodal lymphomas. Dr. Ferreri is Associate Editor of the ESO/START Project and of “Haematological Oncology” and Faculty of the European School of Oncology. Dr. Ferreri is a member of EHA, ESMO, ASH, and ASCO.


Bibliographic Information

  • Book Title: Resistance of Targeted Therapies Excluding Antibodies for Lymphomas

  • Editors: Andrés J. M. Ferreri

  • Series Title: Resistance to Targeted Anti-Cancer Therapeutics

  • DOI: https://doi.org/10.1007/978-3-319-75184-9

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing AG, part of Springer Nature 2018

  • Hardcover ISBN: 978-3-319-75183-2Published: 13 April 2018

  • Softcover ISBN: 978-3-030-09165-1Published: 26 January 2019

  • eBook ISBN: 978-3-319-75184-9Published: 04 April 2018

  • Series ISSN: 2196-5501

  • Series E-ISSN: 2196-551X

  • Edition Number: 1

  • Number of Pages: XIII, 138

  • Number of Illustrations: 1 b/w illustrations, 13 illustrations in colour

  • Topics: Cancer Research, Molecular Medicine

Buy it now

Buying options

eBook USD 99.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 129.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access