Skip to main content
  • Book
  • © 2019

Management of Bone Metastases

A Multidisciplinary Guide

  • Thoroughly updated reference for the day-to-day management of patients with bones metastases
  • Includes a full description of the integrated oncologic and orthopedic approach to treating patients with bone metastasis
  • Describes the minimally invasive non-surgical therapies for the management of oncology patients

Buy it now

Buying options

eBook USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 129.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

This is a preview of subscription content, log in via an institution to check for access.

Table of contents (27 chapters)

  1. Front Matter

    Pages i-xvi
  2. Biology of Bone Metastases

    1. Front Matter

      Pages 1-1
    2. Pathology of Bone Metastasis

      • Carlo Della Rocca, Claudio Di Cristofano
      Pages 3-11
    3. Bone-Modifying Agents and Anticancer Agents with Bone Effects

      • Daniele Santini, Francesco Pantano, Michele Iuliani, Giulia Ribelli, Paolo Manca, Bruno Vincenzi et al.
      Pages 13-25
    4. Bone-Targeted Therapies in Adjuvant Setting

      • Toni Ibrahim, Federica Recine
      Pages 27-39
  3. Approach to the Patient

    1. Front Matter

      Pages 41-41
    2. How Expected Survival Influences the Choice of Surgical Procedure in Metastatic Bone Disease

      • Panagiotis Tsagozis, Jonathan Forsberg, Henrik C. F. Bauer, Rikard Wedin
      Pages 49-54
    3. The Role of Radiotherapy in Long Bone Metastases and Pelvis

      • Michele Fiore, Carla Germana Rinaldi, Sara Ramella
      Pages 55-63
    4. The Role of Radiotherapy in Spinal Metastases

      • Francesca De Felice, Daniela Musio, Vincenzo Tombolini
      Pages 65-72
    5. Management of Metastases to the Spine and Sacrum

      • Riccardo Ghermandi, Gisberto Evangelisti, Marco Girolami, Valerio Pipola, Stefano Bandiera, Giovanni Barbanti-Bròdano et al.
      Pages 73-92
    6. Metastases to the Long Bones: Algorithm of Treatment

      • Maurizio Scorianz, Franco Gherlinzoni, Domenico A. Campanacci
      Pages 93-102
    7. Metastases to the Pelvis: Algorithm of Treatment

      • Andrea Angelini, Giulia Trovarelli, Pietro Ruggieri
      Pages 103-113
    8. Pathologic Versus Impending Fracture

      • Maria Silvia Spinelli, Andrea Piccioli
      Pages 115-122
  4. Surgery

    1. Front Matter

      Pages 123-123
    2. Osteosynthesis in Metastatic Disease of Long Bones

      • Primo Daolio, Vincenzo Ippolito, Barbara Rossi, Eleonora Marini, Stefano Bastoni
      Pages 125-135
    3. Spinal Metastases: Diagnosis and Management

      • Vincenzo Denaro, Alberto Di Martino
      Pages 137-147
    4. Megaprosthesis for Metastasis of the Lower Limb

      • Carmine Zoccali, Dario Attala, Alessandra Scotto, Roberto Biagini
      Pages 149-157
    5. Metastases to the Pelvis

      • Eduardo J. Ortiz-Cruz, Manuel Peleteiro-Pensado, Irene Barrientos-Ruiz, Rafael Carbonell-Escobar
      Pages 159-165
    6. Megaprosthesis in Metastases of the Shoulder

      • Vincenzo Denaro, Alberto Di Martino
      Pages 167-172

About this book

This highly informative book provides a comprehensive, up-to-date and practical reference for daily clinical practice in the management of patients affected by bone metastases. Written by renowned orthopedic surgeons and leading doctors in the respective fields of expertise, it offers a transversal review of the current medical and surgical treatments to allow a real interdisciplinary approach to the oncologic patient according to the highest current standards.

The book illustrates all the fundamental medical treatments for metastatic bone diseases and provides an overview of pathology issues related to this condition. An entire section is devoted to main different methods of patients approach. It also provides guidance on all current surgical procedures and minimally invasive treatment techniques.

Using a common language and recognizing the different osteoncologic competences, this work allows surgeons, oncologists, radiologists, pathologists and physiatricians to update their expertise and broaden their understanding of how a real team approach can improve the management of these oncology patients.

Reviews

“For the radiologist with an interest in tumour work and impact of skeletal metastases, this is a well written and interesting book. … there are multiple informative images related to surgical management later on. The book is not expensive and for those interested in a more holistic understanding of the patient with metastatic bone disease, it highlights the newer treatments available that go hand in hand with the extended longevity for many cancer patients compared to 20 years ago.” (Prudencia Tyrell, RAD Magazine, September, 2019)

Editors and Affiliations

  • Department of Orthopaedics and Trauma Surgery, University Campus Bio-Medico of Rome, Rome, Italy

    Vincenzo Denaro, Alberto Di Martino

  • General Direction of Health Program, National Ministry of Health of Italy, Rome, Italy

    Andrea Piccioli

About the editors

Prof. Vincenzo Denaro has been Full Professor in orthopaedic surgery and Dean at the University Campus Bio-Medico of Rome, and is one of the leading spine surgeons in Italy. His training included Professor Boni in Pavia, Professor Roy-Camille at the Hopital Pitie Salpetriere in Paris, and Prof. Macnab in Toronto. Being one of the founder members of the Cervical Spine Research Society of Europe, he has been President of the Italian Spine Society. His main fields of interest include the management of patients affected by Spinal and Tumor diseases. He is co-author of the National Guidelines on the management of bone metastases of the Italian Orthopaedic Society (S.I.O.T.), and of the Italian Association of Medical Oncology (A.I.O.M). He is author of more than 300 papers and book chapters, and has edited two books.

Dr. Alberto Di Martino is Assistant Professor in orthopaedics and trauma surgery at University Campus Bio-Medico of Rome. His main fields of interests include spine andtumor surgery, and basic research. He has a PhD in tissue regeneration in Orthopaedics, and in currently involved in the osteoncology unit at the University Campus Bio-Medico of Rome. His training include a Spine research fellowship at Thomas Jefferson University and the Rothman Institute of Philadelphia (USA), and is currently involved in the Spine and Oncology programs with Prof. Vincenzo Denaro at the University Campus Bio-Medico of Rome. He is the Editorial Coordinator of the Italian Orthopaedic Society Bone Metastasis Study Group of the Italian Orthopaedic Society (S.I.O.T.). He has authored more than 80 manuscripts, and is co-author of the National Guidelines on the management of bone metastases of the S.I.O.T., and of the Italian Association of Medical Oncology (A.I.O.M). He currently is board member of several leading journals in the fields of spine and orthopaedics.

Dr. Andrea Piccioli is an orthopaedic surgeon skilled in musculoskeletal oncology, trained at the Memorial Sloan Kettering Cancer Center of New York. He is the Secretary of Italian Society of Orthopedic and Traumatology (S.I.O.T.) and the Coordinator of the Working Group on Bone Metastasis of the Italian Society. He has been Orthopedic Oncologist Consultant in “Palazzo Baleani" Oncologic Unit of Policlinico Umberto I in Rome, and is currently member of the Scientific Committee of the “Istituto Superiore di Sanità”. He is the Director of the 3rd Office for Quality, Clinical Risk and Hospital Program, General Direction of Health Program, National Ministry of Health. He is the author of several scientific papers in the field of orthopaedic oncology and traumatology, and he is also responsible for the S.I.O.T. National Guidelines on Orthopaedic oncology. His main interests are on Musculoskeletal Oncology, and Public Health. 

Bibliographic Information

  • Book Title: Management of Bone Metastases

  • Book Subtitle: A Multidisciplinary Guide

  • Editors: Vincenzo Denaro, Alberto Di Martino, Andrea Piccioli

  • DOI: https://doi.org/10.1007/978-3-319-73485-9

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing AG, part of Springer Nature 2019

  • Hardcover ISBN: 978-3-319-73484-2Published: 11 August 2018

  • Softcover ISBN: 978-3-030-08797-5Published: 11 January 2019

  • eBook ISBN: 978-3-319-73485-9Published: 25 July 2018

  • Edition Number: 1

  • Number of Pages: XVI, 290

  • Number of Illustrations: 44 b/w illustrations, 57 illustrations in colour

  • Topics: Surgical Orthopedics, Surgical Oncology, Rehabilitation Medicine, Radiotherapy, Diagnostic Radiology, Interventional Radiology

Buy it now

Buying options

eBook USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 129.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access