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Infectious Disease

Drug Interactions in Infectious Diseases: Mechanisms and Models of Drug Interactions

Editors: Pai, M.P., Kiser, J.J., Gubbins, P.O., Rodvold, K.A. (Eds.)

  • A definitive resource on food-drug and herb-drug interactions
    Brand new chapter on in vitro modeling of drug interactions
    Fills a gap in the medical literature on the complex relations between acute infection, inflammation, and the risk of drug interactions

Buy this book

eBook $99.00
price for USA in USD (gross)
  • ISBN 978-3-319-72422-5
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $129.00
price for USA in USD
  • ISBN 978-3-319-72421-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

The 4th edition of Drug Interactions in Infectious Diseases is being split into two separate volumes – “Mechanisms and Models of Drug Interactions” and “Antimicrobial Drug Interactions”.

This volume, “Mechanisms and Models of Drug Interactions,” delivers a text that enhances clinical knowledge of the complex mechanisms, risks, and consequences of drug interactions associated with antimicrobials, infection, and inflammation.  The book provides a comprehensive review of basic clinical pharmacology with a focus on metabolism and transporter-mediated drug interactions. The chapters address materials that cannot be retrieved easily in the medical literature, including materials focused on the complex interrelationship of acute infection, inflammation, and the risk of drug interactions in the Drug-Cytokine chapter. The Food-Drug and Herb-Drug interactions chapters remain definitive resources. A new chapter on in vitro modeling of drug interactions is included along with updates on design and data analysis of clinical drug interaction studies. Authoritative discussion of models for regulatory decision-making on drug-drug interactions provides the necessary framework to aid antimicrobial drug development. This concise review of the mechanisms and models of drug interactions provides important insights to health care practitioners as well as scientists in drug development.

About the authors

Manjunath P. Pai, College of Pharmacy, University of Michigan, Ann Arbor, MI 

Jennifer J. Kiser, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO 

Paul O. Gubbins, School of Pharmacy, University of Missouri-Kansas City, Springfield, MO

Keith A. Rodvold, University of Illinois, College of Pharmacy and Medicine, Chicago, IL 

Table of contents (9 chapters)

  • Introduction to Drug-Drug Interactions

    Pai, Manjunath P. (et al.)

    Pages 1-13

  • Mechanisms of Drug Interactions I: Absorption, Metabolism, and Excretion

    Burger, David M. (et al.)

    Pages 15-47

  • Mechanisms of Drug Interactions II: Transport Proteins

    Moss, Darren Michael (et al.)

    Pages 49-85

  • Drug-Food Interactions

    Wenzler, Eric (et al.)

    Pages 87-162

  • Drug-Cytokine Interactions

    Goralski, Kerry B. (et al.)

    Pages 163-204

Buy this book

eBook $99.00
price for USA in USD (gross)
  • ISBN 978-3-319-72422-5
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $129.00
price for USA in USD
  • ISBN 978-3-319-72421-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Drug Interactions in Infectious Diseases: Mechanisms and Models of Drug Interactions
Editors
  • Manjunath P. Pai
  • Jennifer J. Kiser
  • Paul O. Gubbins
  • Keith A. Rodvold
Series Title
Infectious Disease
Copyright
2018
Publisher
Humana Press
Copyright Holder
Springer International Publishing AG
eBook ISBN
978-3-319-72422-5
DOI
10.1007/978-3-319-72422-5
Hardcover ISBN
978-3-319-72421-8
Edition Number
4
Number of Pages
XVI, 326
Number of Illustrations and Tables
3 b/w illustrations, 5 illustrations in colour
Topics