Current Topics in Microbiology and Immunology

Biology of Chlamydia

Editors: Häcker, Georg (Ed.)

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  • Discusses the question of long-term, persistent Chlamydia infection
  • Provides new insights into chlamydial host adaptation
  • Illustrates the complex mechanisms that determine immune recognition, immunopathology and potentially anti-infective protection
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About this book

The genus Chlamydia encompasses a number of species of obligate intracellular bacteria, including important human pathogens like the most common bacterial agent of sexually transmitted disease. This volume reviews current knowledge of chlamydial biology, covering the unusual structure of the bacteria – which alternate between metabolically almost inactive and fast-dividing forms. It also discusses the ways in which Chlamydia manipulates the host cytoskeleton and subverts the host cell’s defence, and illustrates how genomics have begun to uncover the diversity and complexity of chlamydial strains that look very similar but may cause distinct forms of disease. Further, it describes how techniques are now finally being established that can genetically modify Chlamydia, and discusses why such modification is still very difficult and what progress we can expect. Lastly, it presents our current understanding of chlamydial disease: what do we know about chronic infections, what are the mechanisms of inflammatory damage, and what are the prospects of a vaccine? Written be specialists in these various areas, the book is a valuable work of reference for students and scientists with an interest in the molecular, cellular and immunobiology of these fascinating bacteria.

About the authors

Prof. Dr. med. Georg Häcker

Universitätsklinikum Freiburg 

Institut für Medizinische Mikrobiologie und Hygiene

Hermann-Herder-Str. 11

79104 Freiburg

Germany

e-mail: Georg.Haecker@uniklinik-freiburg.de

Phone: +49 761 203-6531

 

Table of contents (9 chapters)

Table of contents (9 chapters)
  • Deconstructing the Chlamydial Cell Wall

    Pages 1-33

    Klöckner, Anna (et al.)

  • One Face of Chlamydia trachomatis: The Infectious Elementary Body

    Pages 35-58

    Cossé, Mathilde M. (et al.)

  • Manipulation of the Host Cell Cytoskeleton by Chlamydia

    Pages 59-80

    Nogueira, Ana T. (et al.)

  • Subversion of Cell-Autonomous Host Defense by Chlamydia Infection

    Pages 81-106

    Fischer, Annette (et al.)

  • The Hidden Genomics of Chlamydia trachomatis

    Pages 107-131

    Hadfield, James (et al.)

Buy this book

eBook n/a
  • ISBN 978-3-319-71232-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
Hardcover n/a
  • ISBN 978-3-319-71230-7
  • Free shipping for individuals worldwide
Softcover n/a
  • ISBN 978-3-030-10031-5
  • Free shipping for individuals worldwide
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Bibliographic Information

Bibliographic Information
Book Title
Biology of Chlamydia
Editors
  • Georg Häcker
Series Title
Current Topics in Microbiology and Immunology
Series Volume
412
Copyright
2018
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing AG, part of Springer Nature
eBook ISBN
978-3-319-71232-1
DOI
10.1007/978-3-319-71232-1
Hardcover ISBN
978-3-319-71230-7
Softcover ISBN
978-3-030-10031-5
Series ISSN
0070-217X
Edition Number
1
Number of Pages
X, 237
Topics