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Topics in Medicinal Chemistry

RNA Therapeutics

Editors: Garner, Amanda L. (Ed.)

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About this book

Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.

Table of contents (9 chapters)

Table of contents (9 chapters)
  • Computational Tools for Design of Selective Small Molecules Targeting RNA: From Small Molecule Microarrays to Chemical Similarity Searching

    Pages 1-16

    Costales, Matthew G. (et al.)

  • A Modular Approach to the Discovery and Affinity Maturation of Sequence-Selective RNA-Binding Compounds

    Pages 17-45

    Miller, Benjamin L.

  • Structure-Based Discovery of Small Molecules Binding to RNA

    Pages 47-77

    Wehler, Thomas (et al.)

  • Approaches for the Discovery of Small Molecule Ligands Targeting microRNAs

    Pages 79-110

    Lorenz, Daniel A. (et al.)

  • Viral RNA Targets and Their Small Molecule Ligands

    Pages 111-134

    Hermann, Thomas

Buy this book

eBook $269.00
price for USA in USD (gross)
  • ISBN 978-3-319-68091-0
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $349.99
price for USA in USD
  • ISBN 978-3-319-68090-3
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
Softcover $349.99
price for USA in USD
  • ISBN 978-3-319-88546-9
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
RNA Therapeutics
Editors
  • Amanda L. Garner
Series Title
Topics in Medicinal Chemistry
Series Volume
27
Copyright
2018
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing AG
eBook ISBN
978-3-319-68091-0
DOI
10.1007/978-3-319-68091-0
Hardcover ISBN
978-3-319-68090-3
Softcover ISBN
978-3-319-88546-9
Series ISSN
1862-2461
Edition Number
1
Number of Pages
VII, 259
Number of Illustrations
45 illustrations in colour
Topics

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