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Springer Theses

Design and Evaluation of Plasmonic/Magnetic Au-MFe2O4 (M-Fe/Co/Mn) Core-Shell Nanoparticles Functionalized with Doxorubicin for Cancer Therapeutics

Authors: Manisekaran, Ravichandran

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  • Provides an introduction to nanomedicine and cancer therapy before exploring important biomedical applications
  • Provides a pathway to future studies on the synthesis and surface modification of nanomedicine in the cancer therapy field
  • Explores novel hybrid nanomaterials for efficient designing of multifunctional nanoflotillas
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eBook $109.00
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  • ISBN 978-3-319-67609-8
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $139.99
price for USA in USD
Softcover $139.99
price for USA in USD
About this book

This thesis documents the development of a multifunctional nanoparticle system to enhance the chemotherapeutic efficiency of anti-cancer drugs, and contributes to research that helps decrease the side-effects in cancer patients while simultaneously increasing their survival rates. The work begins with an introduction to nanomedicine and cancer therapy, and contains a literature review on magnetic, gold, and core-shell nanoparticles. It also covers synthesis techniques, properties, various surface modifications, and the importance of magnetic and gold nanoparticles. The author dedicates a chapter to characterization techniques, experimental setup, and cell cultivation techniques for in-vitro studies. Further chapters describe the background, characterizations, and applications of multifunctional magnetite coated gold core-shell nanoparticles, and the doping of cobalt to magnetite and manganese to magnetite nanoparticles. The important highlight of this research was the control of the size, shape, composition, and surface chemistry of nanoparticles.

About the authors

Ravichandran Manisekaran received his degrees from Thiruvalluvar Univeersity, B.Sc in Biochemistry (2008) and M.Sc. in Medical Bionanotechnology from Chettinad University (2010). Recently, he received his PhD in the field of Nanoscience and Nanotechnology (March 2017), from the Center for Research and Advanced Studies of the National Polytechnic Institute (CINVESTAV-IPN), Zacatenco, Mexico City. He will be joining as a research associate in the Nanobio-optics laboratory, Center for Applied Physics and Advanced Technology (CFATA), UNAM campus, Juriquilla. His current research interests are focused on the use of surface functionalized multifunctional nanoparticles for various biomedical applications such as targeted drug delivery, hyperthermia, contrast agents, thermal ablation, electrospinning and biosensing. He was awarded a CONACYT fellowship for carrying out his doctoral research in CINVESTAV-IPN from 2013-2017.

Table of contents (7 chapters)

Table of contents (7 chapters)
  • Introduction to Nanomedicine and Cancer Therapy

    Pages 1-36

    Manisekaran, Ravichandran

  • Literature Survey on Magnetic, Gold, and Core-Shell Nanoparticles

    Pages 37-72

    Manisekaran, Ravichandran

  • Characterization Techniques, Experimental Setup, and Cell Cultivation

    Pages 73-90

    Manisekaran, Ravichandran

  • Designing a Nanocargo with Fe3O4@Au: A Tri-pronged Mechanism for MR Imaging, Synaphic Drug-Delivery, and Apoptosis Induction in Cancer Cells

    Pages 91-113

    Manisekaran, Ravichandran

  • Multiple Iterative Seeding of Surface Plasmon Enhanced Cobalt-Iron Oxide Nanokernels for Cancer Theranostics

    Pages 115-138

    Manisekaran, Ravichandran

Buy this book

eBook $109.00
price for USA in USD
  • ISBN 978-3-319-67609-8
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $139.99
price for USA in USD
Softcover $139.99
price for USA in USD
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Bibliographic Information

Bibliographic Information
Book Title
Design and Evaluation of Plasmonic/Magnetic Au-MFe2O4 (M-Fe/Co/Mn) Core-Shell Nanoparticles Functionalized with Doxorubicin for Cancer Therapeutics
Authors
Series Title
Springer Theses
Copyright
2018
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing AG
eBook ISBN
978-3-319-67609-8
DOI
10.1007/978-3-319-67609-8
Hardcover ISBN
978-3-319-67608-1
Softcover ISBN
978-3-319-88457-8
Series ISSN
2190-5053
Edition Number
1
Number of Pages
XL, 168
Number of Illustrations
7 b/w illustrations, 84 illustrations in colour
Topics