Design and Evaluation of Plasmonic/Magnetic Au-MFe2O4 (M-Fe/Co/Mn) Core-Shell Nanoparticles Functionalized with Doxorubicin for Cancer Therapeutics
Authors: Manisekaran, Ravichandran
Free Preview- Provides an introduction to nanomedicine and cancer therapy before exploring important biomedical applications
- Provides a pathway to future studies on the synthesis and surface modification of nanomedicine in the cancer therapy field
- Explores novel hybrid nanomaterials for efficient designing of multifunctional nanoflotillas
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- About this book
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This thesis documents the development of a multifunctional nanoparticle system to enhance the chemotherapeutic efficiency of anti-cancer drugs, and contributes to research that helps decrease the side-effects in cancer patients while simultaneously increasing their survival rates. The work begins with an introduction to nanomedicine and cancer therapy, and contains a literature review on magnetic, gold, and core-shell nanoparticles. It also covers synthesis techniques, properties, various surface modifications, and the importance of magnetic and gold nanoparticles. The author dedicates a chapter to characterization techniques, experimental setup, and cell cultivation techniques for in-vitro studies. Further chapters describe the background, characterizations, and applications of multifunctional magnetite coated gold core-shell nanoparticles, and the doping of cobalt to magnetite and manganese to magnetite nanoparticles. The important highlight of this research was the control of the size, shape, composition, and surface chemistry of nanoparticles.
- About the authors
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Ravichandran Manisekaran received his degrees from Thiruvalluvar Univeersity, B.Sc in Biochemistry (2008) and M.Sc. in Medical Bionanotechnology from Chettinad University (2010). Recently, he received his PhD in the field of Nanoscience and Nanotechnology (March 2017), from the Center for Research and Advanced Studies of the National Polytechnic Institute (CINVESTAV-IPN), Zacatenco, Mexico City. He will be joining as a research associate in the Nanobio-optics laboratory, Center for Applied Physics and Advanced Technology (CFATA), UNAM campus, Juriquilla. His current research interests are focused on the use of surface functionalized multifunctional nanoparticles for various biomedical applications such as targeted drug delivery, hyperthermia, contrast agents, thermal ablation, electrospinning and biosensing. He was awarded a CONACYT fellowship for carrying out his doctoral research in CINVESTAV-IPN from 2013-2017.
- Table of contents (7 chapters)
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Introduction to Nanomedicine and Cancer Therapy
Pages 1-36
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Literature Survey on Magnetic, Gold, and Core-Shell Nanoparticles
Pages 37-72
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Characterization Techniques, Experimental Setup, and Cell Cultivation
Pages 73-90
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Designing a Nanocargo with Fe3O4@Au: A Tri-pronged Mechanism for MR Imaging, Synaphic Drug-Delivery, and Apoptosis Induction in Cancer Cells
Pages 91-113
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Multiple Iterative Seeding of Surface Plasmon Enhanced Cobalt-Iron Oxide Nanokernels for Cancer Theranostics
Pages 115-138
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Table of contents (7 chapters)
- Download Preface 1 PDF (101.5 KB)
- Download Sample pages 1 PDF (925.7 KB)
- Download Table of contents PDF (149.4 KB)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Design and Evaluation of Plasmonic/Magnetic Au-MFe2O4 (M-Fe/Co/Mn) Core-Shell Nanoparticles Functionalized with Doxorubicin for Cancer Therapeutics
- Authors
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- Ravichandran Manisekaran
- Series Title
- Springer Theses
- Copyright
- 2018
- Publisher
- Springer International Publishing
- Copyright Holder
- Springer International Publishing AG
- eBook ISBN
- 978-3-319-67609-8
- DOI
- 10.1007/978-3-319-67609-8
- Hardcover ISBN
- 978-3-319-67608-1
- Softcover ISBN
- 978-3-319-88457-8
- Series ISSN
- 2190-5053
- Edition Number
- 1
- Number of Pages
- XL, 168
- Number of Illustrations
- 7 b/w illustrations, 84 illustrations in colour
- Topics
