Overview
Unparallel bird’s eye views of highly regulated molecular signaling or biological laws in effective immunity (Yin or tumoricidal vs. Yang or tumorigenic) that protect health
Propose and compare differential bioenergetic requirements and Yin-Yang pathways from conception to age-associated diseases and cancers
Address notable biological heterogeneities, defects and knowledge gaps to bring order to current chaos in cancer science
Includes supplementary material: sn.pub/extras
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Table of contents (6 chapters)
Keywords
About this book
Our knowledge of the fascinating biology of immunity in health or chronic diseases is fragmentary, chaotic and confusing, particularly for cancer science. Lack of progress in curing majority of chronic diseases or cancer is primarily due to the fact that scientists work on isolated molecules/cells or topics that are funded and promoted by decision makers in medical/cancer establishment. Despite existence of over 25 million articles on cancer-related topics, cancer biology and cure remain mysteries to be solved. After a century of cancer research, the failure rates of therapies for solid tumors are 90% (+/-5). Current reductionist views on cancer science are irresponsible, shut-gun approaches and create chaos. Outcomes are loss of millions of precious lives and economic drain to society. Very little is known about initial events that disturb effective immunity whose function is to monitor and arrest growth of cancerous cells or defend against other external or internal hazardous agents that threaten body’s survival.
The author demonstrates the serious need for systematic understanding of how immune disruptors and aging process would alter effective immunity. Outcomes of proposed orderly studies are expected to provide logical foundations for cost-effective strategies to promote immunity toward a healthier society. The policy makers and medical/cancer establishment are urged to return to the common sense that our Forefathers used to serve the public.
Authors and Affiliations
Bibliographic Information
Book Title: Inflammation, Aging and Cancer
Book Subtitle: Biological Injustices to Molecular Village of Immunity that Guard Health
Authors: Mahin Khatami
DOI: https://doi.org/10.1007/978-3-319-66475-0
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing AG 2017
Hardcover ISBN: 978-3-319-66473-6Published: 25 January 2018
Softcover ISBN: 978-3-319-88251-2Published: 19 March 2019
eBook ISBN: 978-3-319-66475-0Published: 17 January 2018
Edition Number: 1
Number of Pages: XVI, 389
Number of Illustrations: 5 b/w illustrations, 52 illustrations in colour
Topics: Cancer Research