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Acute Promyelocytic Leukemia

A Clinical Guide

Editors: Abla, Oussama, Lo Coco, Francesco, Sanz, Miguel A. (Eds.)

  • First comprehensive text on acute promyelocytic leukemia in the last ten years
  • Summarizes historical, current, and future treatment strategies
  • Highlights the most recent therapeutic recommendations for relapsed disease 
  • Written by top experts in the field
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Buy this book

eBook $99.00
price for USA in USD (gross)
  • ISBN 978-3-319-64257-4
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $129.00
price for USA in USD
  • ISBN 978-3-319-64256-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book provides a comprehensive overview on the clinical issues and biology of acute promyelocytic leukemia (APL) and on the molecular mechanisms of targeted therapy with ATRA and ATO. The text covers major topics such as the pathophysiology of APL coagulopathy, biologic and clinical differences between children and adults with APL, and the role of minimal residual disease monitoring. Additionally, the book summarizes historical, current, and future treatment strategies in both adults and children, while highlighting the most recent therapeutic recommendations for relapsed disease and the evolving indications for autologous and allogeneic stem cell transplant. This volume also features chapters focusing on secondary APL and therapy, late effects, rare presentations such as APL in the elderly and during pregnancy, and rare APL variants that may represent therapeutic challenges.

Written by top experts in the field, Acute Promyelocytic Leukemia: A Clinical Guide is a valuable resource for clinicians and researchers who treat and investigate this disease in children and adults.

About the authors

Oussama Abla, MD

The Hospital for Sick Children and University of Toronto

Division of Hematology/Oncology

Toronto, ON

Canada

 

Francesco Lo-Coco, MD

Professor of Hematology

University of Tor Vergata

Rome

Italy

 

Miguel A. Sanz, MD

Centro de Investigación Biomédica en Red de Cáncer

Madrid

Spain

Table of contents (21 chapters)

  • History of Acute Promyelocytic Leukemia

    Degos, Laurent, M.D., Ph.D.

    Pages 1-16

  • Molecular Targets of Treatment in APL

    Rahmé, Ramy, M.D. (et al.)

    Pages 17-27

  • The Leukemic Stem Cell

    Vlachou, Thalia, Ph.D. (et al.)

    Pages 29-40

  • Molecular Genetics of APL

    Mendez, Lourdes, M.D., Ph.D. (et al.)

    Pages 41-53

  • APL Coagulopathy

    Falanga, Anna, M.D. (et al.)

    Pages 55-70

Buy this book

eBook $99.00
price for USA in USD (gross)
  • ISBN 978-3-319-64257-4
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $129.00
price for USA in USD
  • ISBN 978-3-319-64256-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Acute Promyelocytic Leukemia
Book Subtitle
A Clinical Guide
Editors
  • Oussama Abla
  • Francesco Lo Coco
  • Miguel A. Sanz
Copyright
2018
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing AG, part of Springer Nature
eBook ISBN
978-3-319-64257-4
DOI
10.1007/978-3-319-64257-4
Hardcover ISBN
978-3-319-64256-7
Edition Number
1
Number of Pages
XII, 274
Number of Illustrations
10 b/w illustrations, 29 illustrations in colour
Topics