Platelet Rich Plasma in Orthopaedics and Sports Medicine

1. Front Matter

   Pages 1-11

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2. Platelets at the Interface between Inflammation and Tissue Repair

   • Nurden A. T., Nurden P.

   Pages 13-27

3. Characterization of Plasma Rich in Growth Factors (PRGF): components and formulations

   • Anitua E., Prado R., Nurden A. T., Nurden P.

   Pages 29-45

4. Repair and Regeneration: Connecting the Dots Among Coagulation, Immune System, the Sensory Nervous System and Fibrogenesis

   • Padilla S., Sánchez M., Padilla I., Anitua E.

   Pages 47-63

5. Effects of Plasma Rich in Growth Factors on Cells and Tissues of Musculoskeletal System: from Articular Cartilage to Muscles and Nerves

   • S. Padilla, M. Sánchez, E. Anitua

   Pages 65-81

6. Molecular Intervention with Plasma-Rich Growth Factors to Enhance Muscle Perfusion and Tissue Remodeling in Ischemic Diseases

   • B. Pelacho, A. Pérez, F. Prósper

   Pages 83-97

7. Endoret® (PRGF®) Application in the Oral and Maxillofacial Field

   • E. Anitua, L. Piñas, H. M. Alkhraisat

   Pages 99-123

8. The Scientific Rationale to Apply Plasma Rich in Growth Factors in Joint Tissue Pathologies: Knee Osteoarthritis

   • Padilla S., Anitua E., Fiz N., Pompei O., Azofra J., Sánchez M.

   Pages 125-143

9. A New Approach to Treat Joint Injuries: Combination of Intra-Articular and Intraosseous Injections of Platelet Rich Plasma

   • Sánchez M., Anitua E., Delgado D., Sanchez P., Prado R., Prosper F. et al.

   Pages 145-161

10. Knee Osteoarthritis: One versus Two Cycles of PRGF Infiltrations Treatment

    • Vaquerizo V., Ruiz de Castañeda MM.

    Pages 163-173

11. PRGF on Sports-Related Ligament Injuries

    • Cugat R., Cuscó X., Seijas R., Barastegui D., Álvarez-Díaz P., Alentorn-Geli E. et al.

    Pages 175-189

12. Tendinopathy and its Treatment: the Rationale and Pitfalls in the Clinical Application of PRP

    • Wang J., Zhou Y., Nirmala X.

    Pages 191-209

13. Infiltrations of PRGF to Treat Ligament and Tendon Injuries in the Hip and Pelvis

    • Kraeutler MJ., Garabekyan T., Mei-Dan O.

    Pages 211-223

14. A Novel and Versatile Adjuvant Biologic Therapy in the Management of Neuropathies

    • Sánchez M., Anitua E., Delgado D., Garate A., Bilbao AM., Sánchez P. et al.

    Pages 225-239

15. PRGF Molecular Intervention: a Bridge from Spontaneity to Muscle Repair

    • Sánchez M., Anitua E., Aizpurua B., Delgado D., Sánchez P., Guadilla J. et al.

    Pages 241-257

16. Minimally Invasive PRGF Treatment for Low Back Pain and Degenerative Disc Disease

    • Kirchner F., Anitua E.

    Pages 259-275

17. Education and Standardization of Orthobiologics: Past, Present & future

    • Sampson S., Vincent H., Ambach M.

    Pages 277-287

This book provides a comprehensive, state-of-the art summary of platelet rich plasmas (PRPs) in the field of regenerative medicine. The book begins with an overview of the  basic science behind PRP, describing the role of platelets and growth factors followed by the most important biological effects expected from the use of PRPs.

Platelet Rich Plasma in Orthopaedics, Sports Medicine and Maxillofacial Surgery includes numerous contributions detailing the current use of PRPs in clinical practice. From the origins in oral and maxillofacial surgery, to the latest advances in orthopaedics and sports medicine including the use of Platelet Rich Growth Factors (PRGF) in muscle, bone, tendon, ligament and nerve injuries, this book provides a wide scope of the topic. The volume concludes with chapters from experts in biology, orthopaedics, oral and maxillofacial surgery, where the convergence of expertise is leading to unprecedented insights into how to minutely control the invivo fate and function of PRGF. This book will provide a useful resource for physicians and researchers interested in learning more about this rapidly growing area of biomedical treatment.  

• Plasma Rich
• Growth Factors
• Musculoskeletal Tissues Repair
• Translational medicine
• Sports Injuries
• Trauma Surgery

• Director of the University Institute for Regenerative Medicine and Oral, Implantology (UIRMI) from the University of Basque Country (UPV/EHU), Vitoria, Spain

  Eduardo Anitua

• Hospital Quirón, Artroscopia GC, Barcelona , Spain

  Ramón Cugat

• Arthroscopic Surgery Unit, Hospital Vithas San José, Vitoria, Spain

  Mikel Sánchez

Eduardo Anitua, MD, DDS, PhD is Director of the Instituto Eduardo Anitua, Vitoria, Spain. He has lectured at more than 500 courses and conferences on implants, prosthesis, dental aesthetics and tissue regeneration in Spain and abroad in Europe, United States, South America and Asia. In addition to lecturing, he has authored and co-authored more than 10 books and book chapters and more than 100 research and review articles in National and International journals including TRENDS, PPAD, JOMI, JOI, Clinic, Oral Implant Research, Thrombosis and Haemostasis. 

Ramón Cugat, MD is a Specialist in Orthopaedic Surgery and Traumatology at Hospital Quirón, Barcelona, Spain. He is Associate Professor at the Faculty of Medicine of the University of Barcelona and the Universidad CEU Cardenal Herrera Valencia, as well as co-director of the Chair of Medicine and Regenerative Surgery created in 2013 by the Garcia Cugat Foundation and the Universidad CEU Cardenal Herrera Valencia. He also belongs tothe international team of faculty of the International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports Meidcine (ISAKOS).

Mikel Sanchez, MD is scientific director and medical Unit Arthroscopic Surgery (UCA) of Vithas Hospital San José, Vitoria-Gasteiz. In addition to the UCA, he was the founder of the first unit Biological Therapy (UTB) in Vitoria-Gasteiz.  His scientific merits include his pioneering work in the advancement of arthroscopic surgery in Spain and Europe, and being the first physician to understand the therapeutic potential of growth factors in the different diseases of the locomotor system, along with developing protocols for its application in traumatology.

 

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