Advances in Experimental Medicine and Biology

Pulmonary Vasculature Redox Signaling in Health and Disease

Editors: Wang, Yong Xiao (Ed.)

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  • Written by a collection of international experts in basic and translations research in pulmonary vasculature
  • Comprehensive review of current and emerging developments in the field
  • Provides invaluable information on an important signaling pathway with a critical role in nearly all pulmonary diseases
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eBook $169.00
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  • ISBN 978-3-319-63245-2
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Hardcover $219.99
price for USA in USD
  • ISBN 978-3-319-63244-5
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  • Usually ready to be dispatched within 3 to 5 business days, if in stock
Softcover $219.99
price for USA in USD
  • ISBN 978-3-319-87507-1
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
About this book

The main goal of this book is to form a high-quality platform in which well-known and emerging pioneering basic, translational and clinical scientists can present their latest, exciting findings in the studies of redox signaling in the pulmonary vasculature. Content from outstanding investigators with unique expertise and skills of molecular and cell biology, biochemistry, physiology, pharmacology, biophysics, biotechnology and medicine will update our current out-of-date concepts with new knowledge. Rapidly increasing scientific studies have gathered a large volume of novel and important information on redox signaling in healthy and diseased pulmonary vasculature. This volume covers the need for a cohesive book to display state-of-the-art advances in the field.   

The second major aim of this book is to help direct future research. Redox signaling is a major molecular process involved in almost every physiologic cellular response in the pulmonary vasculature including energy metabolism, host defense, gene expression, contraction, proliferation, and migration. Aberrancy in this important signaling pathway leads to a critical role in the development of nearly all pulmonary diseases, such as pulmonary hypertension, cor pulmonale, pulmonary edema, and vasculitis, among others.  


About the authors

Dr. Yong-Xiao Wang is a Full Professor in the Department of Molecular and Cellular Physiology at Albany Medical College, Albany, New York, USA. He received his M.D. at the Wannan Medical College (China), Ph.D. at the Fourth Military Medical University (China), and postdoctoral training at the Technical University of Munich (Germany) as well as the University of Pennsylvania (USA). Dr. Wang’s primary research interests have focused on basic, translational, and drug discovery research concerning cardiac arrhythmias and hypertrophy, pulmonary hypertension, asthma, and diabetes for over 30 years. In particular, he has had extensive research experience in the studies of the molecular geneses, regulatory mechanisms, network pathways, physiological functions, and the critical roles of calcium, redox, inflammatory, and other signaling in the aforementioned illnesses. Dr. Wang has been the corresponding author, first author, and key contributor in numerous publications in highly peer-reviewed journals including Antioxid Redox Signal, Proc Natl Acad Sci USA, Free Radic Biol Med, Cell Calcium, J Gen Physiol, J Biol Chem, FASEB J, Nature, Circ Res, and more. He has been the editor of several academic books in the field including a recent one entitled “Calcium Signaling in Airway Smooth Muscle Cells” that was published by Springer in 2014. Dr. Wang has been the principal investigator on multiple research grants and awards from the National Institutes of Health, American Heart Association, American Diabetes Association, and other agencies. He has collaborated with numerous well-known scientists, served on various grant review panels, been the Editor-In-Chief and Editorial Board Member for several scientific journals, and trained a number of scholars, some of whom have become well-known independent investigators in the field.

Table of contents (26 chapters)

Table of contents (26 chapters)
  • Adventitial Fibroblast Nox4 Expression and ROS Signaling in Pulmonary Arterial Hypertension

    Pages 1-11

    Barman, Scott A., Ph.D., FAHA (et al.)

  • Role of Transcription Factors in Pulmonary Artery Smooth Muscle Cells: An Important Link to Hypoxic Pulmonary Hypertension

    Pages 13-32

    Mise, Annarita (et al.)

  • Molecular Basis of Nitrative Stress in the Pathogenesis of Pulmonary Hypertension

    Pages 33-45

    Evans, Colin E. (et al.)

  • Pentose Shunt, Glucose-6-Phosphate Dehydrogenase, NADPH Redox, and Stem Cells in Pulmonary Hypertension

    Pages 47-55

    Hashimoto, Ryota (et al.)

  • Redox Regulation of the Superoxide Dismutases SOD3 and SOD2 in the Pulmonary Circulation

    Pages 57-70

    Hernandez-Saavedra, Daniel, Ph.D. (et al.)

Buy this book

eBook $169.00
price for USA in USD
  • ISBN 978-3-319-63245-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-3-319-63244-5
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
Softcover $219.99
price for USA in USD
  • ISBN 978-3-319-87507-1
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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Bibliographic Information

Bibliographic Information
Book Title
Pulmonary Vasculature Redox Signaling in Health and Disease
Editors
  • Yong Xiao Wang
Series Title
Advances in Experimental Medicine and Biology
Series Volume
967
Copyright
2017
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing AG
eBook ISBN
978-3-319-63245-2
DOI
10.1007/978-3-319-63245-2
Hardcover ISBN
978-3-319-63244-5
Softcover ISBN
978-3-319-87507-1
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XXI, 422
Number of Illustrations
16 b/w illustrations, 41 illustrations in colour
Topics