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Current Topics in Microbiology and Immunology

Viruses, Genes, and Cancer

Editors: Hunter, Eric, Bister, Klaus (Eds.)

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  • Includes a foreword by the Nobel laureates J. Michael Bishop and Harold Varmus
  • Casts new light on the role of viruses and genes in the etiology of human cancer
  • Discusses the latest developments in HIV vaccine development
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eBook $139.00
price for USA in USD (gross)
  • ISBN 978-3-319-61804-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-3-319-61803-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $179.99
price for USA in USD
  • ISBN 978-3-319-87167-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This volume focuses on virus-host cell interactions, cellular genes acquired or modulated by viruses, the pathological effects of these interactions, and therapeutic interventions. Several chapters specifically address the role of viruses and genes – such as oncogenes, proto-oncogenes, or tumor suppressor genes – in the etiology of human cancer. Oncogenic signaling by PI3 kinase, mTOR, Akt, or the major cancer drivers MYC and RAF, and the role of tumor suppressors like p53, are discussed in detail. The volume also explores the emerging role of noncoding RNAs such as microRNAs in tumorigenesis and cancer therapeutics, and offers new insights into the role of HIV-host interactions relevant to pathogenesis and treatment. Gathering contributions written by leading scientists in their respective fields, the volume offers a valuable resource for researchers and clinicians alike.

About the authors

Eric Hunter, PhD, is a Professor of Pathology and Laboratory Medicine and a Georgia Research Alliance Eminent Scholar, based in Atlanta, GA, USA
Klaus Bister, PhD, is a Professor Emeritus of Biochemistry of University of Innsbruck, Austria, and a Professor Adjunct of The Scripps Research Institute, La Jolla, CA, USA  

Table of contents (8 chapters)

Table of contents (8 chapters)
  • Exchange of Genetic Sequences Between Viruses and Hosts

    Pages 1-29

    Weiss, Robin A.

  • Virus-Host Gene Interactions Define HIV-1 Disease Progression

    Pages 31-63

    Monaco, Daniela C. (et al.)

  • Sequencing the Biology of Entry: The Retroviral env Gene

    Pages 65-82

    Swanstrom, Ronald (et al.)

  • Infectious Agents in Bovine Red Meat and Milk and Their Potential Role in Cancer and Other Chronic Diseases

    Pages 83-116

    Hausen, Harald (et al.)

  • MYC and RAF: Key Effectors in Cellular Signaling and Major Drivers in Human Cancer

    Pages 117-151

    Stefan, Eduard (et al.)

Buy this book

eBook $139.00
price for USA in USD (gross)
  • ISBN 978-3-319-61804-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-3-319-61803-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $179.99
price for USA in USD
  • ISBN 978-3-319-87167-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Viruses, Genes, and Cancer
Editors
  • Eric Hunter
  • Klaus Bister
Series Title
Current Topics in Microbiology and Immunology
Series Volume
407
Copyright
2017
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing AG
eBook ISBN
978-3-319-61804-3
DOI
10.1007/978-3-319-61804-3
Hardcover ISBN
978-3-319-61803-6
Softcover ISBN
978-3-319-87167-7
Series ISSN
0070-217X
Edition Number
1
Number of Pages
XIII, 221
Topics