The Receptors

G-Protein-Coupled Receptor Dimers

Editors: Herrick-Davis, Katharine, Milligan, Graeme, Di Giovanni, Giuseppe (Eds.)

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  • Comprehensive overview of the major GCPR dimers 
  • Contributors are some of the leading experts in this field 
  • Addresses both typical and pathological aspects and explores therapeutic potential
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eBook $189.00
price for USA in USD (gross)
  • ISBN 978-3-319-60174-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.99
price for USA in USD
  • ISBN 978-3-319-60172-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $249.99
price for USA in USD
  • ISBN 978-3-319-86795-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

G-protein-coupled receptors (GPCRs) are believed to be the largest family of membrane proteins involved in signal transduction and cellular responses. They dimerize (form a pair of macromolecules) with a wide variety of other receptors. The proposed book will provide a comprehensive overview of GPCR dimers, starting with a historical perspective and including, basic information about the different dimers, how they synthesize, their signaling properties, and the many diverse physiological processes in which they are involved.  In addition to presenting information about healthy GPCR dimer activity, the book will also include a section on their pathology and therapeutic potentials.

About the authors

Katharine Herrick-Davis is Professor of Neuroscience and Experimental Therapeutics at Albany Medical College, Albany, USA. Her research has focused on investigating receptor dimerization and how it affects receptor function using the 5-HT2C receptor as a model system. 
Graeme Milligan is Professor of Molecular Pharmacology, University of Glasgow, U.K. he is the Dean of Research, College of Medical, Veterinary and Life Sciences, University of Glasgow. His main research group centres on the function, structure and regulation of GPCRs and their interacting proteins. 
Giuseppe Di Giovanni is Professor of Human Physiology, University of Malta, Malta. He is the President of the Malta Neuroscience Network and Treasurer of the Mediterranean Neuroscience Society. His research has focused on the pathophysiology of the monoaminergic systems in different neuropsychiatric disorders, such as Parkinson's disease, depression, drug of abuse and epilepsy.

Table of contents (20 chapters)

Table of contents (20 chapters)
  • Historical Perspectives: From Monomers to Dimers and Beyond, an Exciting Journey in the World of G Protein-Coupled Receptors

    Rossi, Mario, Ph.D. (et al.)

    Pages 3-14

  • The Use of Spatial Intensity Distribution Analysis to Examine G Protein-Coupled Receptor Oligomerization

    Ward, Richard J., Ph.D. (et al.)

    Pages 15-38

  • Advanced Microscopy Techniques

    Raicu, Valerica, Ph.D. (et al.)

    Pages 39-75

  • Class A GPCR: Light Sensing G Protein-Coupled Receptor – Focus on Rhodopsin Dimer

    Jastrzebska, Beata, Ph.D.

    Pages 79-97

  • Extreme Vetting of Dopamine Receptor Oligomerization

    Asher, Wesley B., Ph.D. (et al.)

    Pages 99-127

Buy this book

eBook $189.00
price for USA in USD (gross)
  • ISBN 978-3-319-60174-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.99
price for USA in USD
  • ISBN 978-3-319-60172-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $249.99
price for USA in USD
  • ISBN 978-3-319-86795-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
G-Protein-Coupled Receptor Dimers
Editors
  • Katharine Herrick-Davis
  • Graeme Milligan
  • Giuseppe Di Giovanni
Series Title
The Receptors
Series Volume
33
Copyright
2017
Publisher
Humana Press
Copyright Holder
Springer International Publishing AG
eBook ISBN
978-3-319-60174-8
DOI
10.1007/978-3-319-60174-8
Hardcover ISBN
978-3-319-60172-4
Softcover ISBN
978-3-319-86795-3
Series ISSN
1048-6909
Edition Number
1
Number of Pages
XVII, 501
Number of Illustrations
12 b/w illustrations, 58 illustrations in colour
Topics