Histiocytic Disorders

Editors: Abla, Oussama, Janka, Gritta (Eds.)

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  • First comprehensive book on histiocytic disorders in over ten years
  • Features the most recent advances and treatment strategies for common and uncommon histiocytic disorders
  • Written by international experts in the field
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eBook $119.00
price for USA in USD (gross)
  • ISBN 978-3-319-59632-7
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $159.99
price for USA in USD
  • ISBN 978-3-319-59631-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $159.99
price for USA in USD
  • ISBN 978-3-319-86667-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This volume provides a comprehensive and world-class review of the field of histiocytic neoplasms and hemophagocytic lymphohistiocytosis (HLH). It reviews all the advances in the field of histiocytoses during the last ten years, particularly with regards to the genomic findings in LCH and other histiocytic neoplasms and the new suggested classification of the histiocytic disorders. Additionally, it features a state-of-the art update on the most recent treatment strategies for LCH, including the results of the last LCH-III international trial, salvage therapies such as reduced-intensity conditioning (RIC) stem cell transplant (SCT), and targeted therapies with BRAF and MEK inhibitors, as well as the challenging cases of CNS-neurodegenerative LCH and its therapeutic perspectives. For primary and secondary HLH the book updates the most recent genetic and pathophysiological findings, including macrophage-activation syndrome (MAS), and includes a special chapter on HLH in adults. Treatment chapters encompass therapy for newly diagnosed HLH and refractory disease as well as stem-cell transplantation and novel therapies. The text also highlights the most recent advances in the treatment of the uncommon histiocytic disorders, such as Erdheim-Chester disease (ECD), Juvenile xanthogranuloma (JXG) and JXG-like conditions, Rosai-Dorfman disease (RDD), and the very rare malignant histiocytoses.
Written by international experts in the field, Histiocytic Disorders is a valuable resource for clinicians, researchers, fellows and residents who are interested in or manage histiocytic disorders in children and adults.

About the authors

Oussama Abla, MDChair, Rare Histiocytoses Steering Committee- Histiocyte Society, Associate Professor of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
Gritta Janka, MD, PhDChair, HLH Steering Committee, Histiocyte Society, Professor emeritus of Pediatrics, University Medical Center Hamburg Eppendorf, Pediatric Hematology and Oncology, Hamburg, Germany

Table of contents (21 chapters)

Table of contents (21 chapters)
  • Pathology of Histiocytic Disorders and Neoplasms and Related Disorders

    Picarsic, Jennifer, MD (et al.)

    Pages 3-50

  • Biology and Genomics of LCH and Related Disorders

    Rollins, Barrett J., MD, PhD

    Pages 53-71

  • Epidemiology and Clinical Manifestations of Langerhans Cell Histiocytosis in Children

    Adam, Etai, MD (et al.)

    Pages 73-85

  • Central Nervous System Langerhans Cell Histiocytosis

    Minkov, Milen, MD, PhD (et al.)

    Pages 87-101

  • First-Line Treatment of Pediatric Langerhans Cell Histiocytosis

    Rodriguez-Galindo, Carlos, MD (et al.)

    Pages 103-118

Buy this book

eBook $119.00
price for USA in USD (gross)
  • ISBN 978-3-319-59632-7
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $159.99
price for USA in USD
  • ISBN 978-3-319-59631-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $159.99
price for USA in USD
  • ISBN 978-3-319-86667-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Histiocytic Disorders
Editors
  • Oussama Abla
  • Gritta Janka
Copyright
2018
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing AG
eBook ISBN
978-3-319-59632-7
DOI
10.1007/978-3-319-59632-7
Hardcover ISBN
978-3-319-59631-0
Softcover ISBN
978-3-319-86667-3
Edition Number
1
Number of Pages
XII, 392
Number of Illustrations
22 b/w illustrations, 74 illustrations in colour
Topics