Progress in Molecular and Subcellular Biology

Centromeres and Kinetochores

Discovering the Molecular Mechanisms Underlying Chromosome Inheritance

Editors: Black, Ben E. (Ed.)

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  • Presents the latest advances concerning the regulation of chromosome segregation during cell division 
  • Covers state-of-the-art techniques employed in the field 
  • Incorporates a wealth of different model systems and species
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eBook $219.00
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  • ISBN 978-3-319-58592-5
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Hardcover $279.99
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Softcover $279.99
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About this book

This book presents the latest advances concerning the regulation of chromosome segregation during cell division by means of centromeres and kinetochores. The authors cover both state-of-the-art techniques and a range of species and model systems, shedding new light on the molecular mechanisms controlling the transmission of genetic material between cell divisions and from parent to offspring. 

The chapters cover five major areas related to the current study of centromeres and kinetochores: 1) their genetic and epigenetic features, 2) key breakthroughs at the molecular, proteomic, imaging and biochemical level, 3) the constitutive centromere proteins, 4) the role of centromere proteins in the physical process of chromosome segregation and its careful orchestration through elaborate regulation, and 5) intersections with reproductive biology, human health and disease, as well as chromosome evolution. The book offers an informative and provocative guide for newcomers as well as those already acquainted with the field.

Table of contents (22 chapters)

Table of contents (22 chapters)
  • Use of Mass Spectrometry to Study the Centromere and Kinetochore

    Samejima, Itaru (et al.)

    Pages 3-27

  • Critical Foundation of the Kinetochore: The Constitutive Centromere-Associated Network (CCAN)

    Hara, Masatoshi (et al.)

    Pages 29-57

  • The Power of Xenopus Egg Extract for Reconstitution of Centromere and Kinetochore Function

    French, Bradley T (et al.)

    Pages 59-84

  • Centrochromatin of Fungi

    Friedman, Steven (et al.)

    Pages 85-109

  • Evolutionary Lessons from Species with Unique Kinetochores

    Drinnenberg, Ines A. (et al.)

    Pages 111-138

Buy this book

eBook $219.00
price for USA in USD (gross)
  • ISBN 978-3-319-58592-5
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.99
price for USA in USD
  • ISBN 978-3-319-58591-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $279.99
price for USA in USD
  • ISBN 978-3-319-86436-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Centromeres and Kinetochores
Book Subtitle
Discovering the Molecular Mechanisms Underlying Chromosome Inheritance
Editors
  • Ben E. Black
Series Title
Progress in Molecular and Subcellular Biology
Series Volume
56
Copyright
2017
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing AG
eBook ISBN
978-3-319-58592-5
DOI
10.1007/978-3-319-58592-5
Hardcover ISBN
978-3-319-58591-8
Softcover ISBN
978-3-319-86436-5
Series ISSN
0079-6484
Edition Number
1
Number of Pages
XI, 554
Number of Illustrations
3 b/w illustrations, 98 illustrations in colour
Topics