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Histamine and Histamine Receptors in Health and Disease

  • Book
  • © 2017

Overview

Editors:
  1. Yuichi Hattori

    1. Department of Molecular and Medical Pharmacology, Graduate School of Medical and Pharmaceutical Sciences, University of Toyama, Toyama, Japan

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    You can also search for this editor in PubMed   Google Scholar

  2. Roland Seifert

    1. Institute of Pharmacology, Medical School of Hannover, Hannover, Germany

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    You can also search for this editor in PubMed   Google Scholar

  • Authors will cover hot topics in the field.
  • Update on last HEP volume on histamine published 25 years ago.
  • Unique topics are combined a in novel way
  • Includes supplementary material: sn.pub/extras
  • Includes supplementary material: sn.pub/extras

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 241)

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-viii
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  2. Analytical Methods for the Quantification of Histamine and Histamine Metabolites

    • Heike Bähre, Volkhard Kaever
    Pages 3-19

  3. Structural Analysis of the Histamine H1 Receptor

    • Mitsunori Shiroishi, Takuya Kobayashi
    Pages 21-30

  4. Molecular Modelling Approaches for the Analysis of Histamine Receptors and Their Interaction with Ligands

    • Andrea Strasser, Hans-Joachim Wittmann
    Pages 31-61

  5. Pharmacological Characterization of Human Histamine Receptors and Histamine Receptor Mutants in the Sf9 Cell Expression System

    • Erich H. Schneider, Roland Seifert
    Pages 63-118

  6. Histamine Release from Mast Cells and Basophils

    • Francesco Borriello, Raffaella Iannone, Gianni Marone
    Pages 121-139

  7. Histamine H2 Receptor in Blood Cells: A Suitable Target for the Treatment of Acute Myeloid Leukemia

    • Federico Monczor, Sabrina Copsel, Natalia Fernandez, Carlos Davio, Carina Shayo
    Pages 141-160

  8. Histamine H1 Receptor Gene Expression and Drug Action of Antihistamines

    • Hiroyuki Fukui, Hiroyuki Mizuguchi, Hisao Nemoto, Yoshiaki Kitamura, Yoshiki Kashiwada, Noriaki Takeda
    Pages 161-169

  9. Histamine Clearance Through Polyspecific Transporters in the Brain

    • Takeo Yoshikawa, Kazuhiko Yanai
    Pages 173-187

  10. Histidine Decarboxylase Knockout Mice as a Model of the Pathophysiology of Tourette Syndrome and Related Conditions

    • Christopher Pittenger
    Pages 189-215

  11. Histamine Food Poisoning

    • Maria Schirone, Pierina Visciano, Rosanna Tofalo, Giovanna Suzzi
    Pages 217-235

  12. Regulation of the Cardiovascular System by Histamine

    • Yuichi Hattori, Kohshi Hattori, Naoyuki Matsuda
    Pages 239-258

  13. Changes in Histidine Decarboxylase, Histamine N-Methyltransferase and Histamine Receptors in Neuropsychiatric Disorders

    • Ling Shan, Ai-Min Bao, Dick F. Swaab
    Pages 259-276

  14. Role of the Histamine H3 Receptor in the Central Nervous System

    • Eberhard Schlicker, Markus Kathmann
    Pages 277-299

  15. Clinical Development of Histamine H4 Receptor Antagonists

    • Robin L. Thurmond, Jennifer Venable, Brad Savall, David La, Sandra Snook, Paul J. Dunford et al.
    Pages 301-320

  16. Allergy, Histamine and Antihistamines

    • Martin K. Church
    Pages 321-331

  17. Histamine and Histamine Receptors in Allergic Dermatitis

    • Hiroshi Ohtsu, Masahiro Seike
    Pages 333-345

  18. Role of the Histamine H4-Receptor in Bronchial Asthma

    • Detlef Neumann
    Pages 347-359

  19. Back Matter

    Pages 361-363
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Keywords

About this book

This ​book provides a comprehensive overview on current histamine and histamine receptor research in context of human health and disease and reflect the multidisciplinary nature of the field. While the editors realize that it is almost impossible to cover the field completely within the constraints of a single HEP volume, nonetheless, all important aspects will be covered in one way or the other. An overarching introductory chapter will link the individual chapters and provide an overview on the field. This chapter will also link the book to the previous HEP volume on histamine receptors and the recent HEP volume on the pharmacology of itch. Great attention will be paid to complementation of existing literature while avoiding undue duplication. The book will cover new methods for analysis of histamine and histamine metabolites, development of methods for histamine receptor analysis, signal transduction, histamine release, regulation of immune cells by histamine, histamine metabolism and associated diseases, regulation of major organ systems by histamine and development of new drugs and experimental tools for the study of histamine receptors.

Editors and Affiliations

  • Department of Molecular and Medical Pharmacology, Graduate School of Medical and Pharmaceutical Sciences, University of Toyama, Toyama, Japan

    Yuichi Hattori

  • Institute of Pharmacology, Medical School of Hannover, Hannover, Germany

    Roland Seifert

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