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Decoding Neural Circuit Structure and Function

Cellular Dissection Using Genetic Model Organisms

Editors: Celik, Arzu, Wernet, Mathias F. (Eds.)

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  • Focuses on the interdisciplinary nature of modern neural circuit dissection: high-resolution anatomy, cellular activity, and behavioral dissection, to assign specific functions to identified, single neurons
  • Compares the progress from vertebrate and invertebrate model systems, both of which provide important, and complementary insights into circuit function
  • Summarizes the most recent work in a very rapidly evolving field: the use of genetic model systems that allow for the manipulation of neural circuits in vivo
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eBook $189.00
price for USA in USD (gross)
  • ISBN 978-3-319-57363-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.99
price for USA in USD
  • ISBN 978-3-319-57362-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $249.99
price for USA in USD
  • ISBN 978-3-319-86143-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book offers representative examples from fly and mouse models to illustrate the ongoing success of the synergistic, state-of-the-art strategy, focusing on the ways it enhances our understanding of sensory processing. The authors focus on sensory systems (vision, olfaction), which are particularly powerful models for probing the development, connectivity, and function of neural circuits, to answer this question: How do individual nerve cells functionally cooperate to guide behavioral responses? Two genetically tractable species, mice and flies, together significantly further our understanding of these processes.

Current efforts focus on integrating knowledge gained from three interrelated fields of research: (1) understanding how the fates of different cell types are specified during development, (2) revealing the synaptic connections between identified cell types (“connectomics”) using high-resolution three-dimensional circuit anatomy, and (3) causal testing of how iden

tified circuit elements contribute to visual perception and behavior.

About the authors

Mathias Wernet is currently a professor of Neurobiology at the Freie University of Berlin. His current research deals with the neural circuitry underlying visual behaviors in Drosophila melanogaster and integrates studies spanning anatomy, behavior, and physiology.

Arzu Celik is a professor of Developmental Neurobiology at Bogazici University in Istanbul, Turkey. Her research focuses on the generation of neuronal diversity and mechanisms of axon guidance in the visual and olfactory systems of Drosophila melanogaster.

Table of contents (21 chapters)

Table of contents (21 chapters)
  • The Current State of the Neuroanatomy Toolkit in the Fruit Fly Drosophila melanogaster

    Pages 3-39

    Gohl, Daryl M. (et al.)

  • Retinal Connectomics

    Pages 41-62

    Briggman, Kevin L.

  • Recent Progress in the 3D Reconstruction of Drosophila Neural Circuits

    Pages 63-89

    Shinomiya, Kazunori (et al.)

  • Connectivity and Circuit Architecture Using Transsynaptic Tracing in Vertebrates

    Pages 91-148

    Miyamichi, Kazunari (et al.)

  • Live Imaging of Connectivity in Developing Neural Circuits in Drosophila

    Pages 149-167

    Özel, Mehmet Neset (et al.)

Buy this book

eBook $189.00
price for USA in USD (gross)
  • ISBN 978-3-319-57363-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.99
price for USA in USD
  • ISBN 978-3-319-57362-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $249.99
price for USA in USD
  • ISBN 978-3-319-86143-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Decoding Neural Circuit Structure and Function
Book Subtitle
Cellular Dissection Using Genetic Model Organisms
Editors
  • Arzu Celik
  • Mathias F. Wernet
Copyright
2017
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing AG
eBook ISBN
978-3-319-57363-2
DOI
10.1007/978-3-319-57363-2
Hardcover ISBN
978-3-319-57362-5
Softcover ISBN
978-3-319-86143-2
Edition Number
1
Number of Pages
XIII, 518
Number of Illustrations
11 b/w illustrations, 81 illustrations in colour
Topics