Irreversible Electroporation in Clinical Practice

Editors: Meijerink, Martijn, Scheffer, Hester J., Narayanan, Govindarajan (Eds.)

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  • Describes the clinical applications of irreversible electroporation/NanoKnife and early clinical results
  • Discusses preclinical research and outcomes
  • Offers full coverage of practical aspects, with highlighting of useful tips and tricks 
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eBook $89.00
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  • ISBN 978-3-319-55113-5
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Hardcover $119.99
price for USA in USD
  • ISBN 978-3-319-55112-8
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  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
Softcover $119.99
price for USA in USD
  • ISBN 978-3-319-85571-4
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
About this book

This book provides a comprehensive overview of the clinical use of irreversible electroporation (IRE) – better known by its commercial name, NanoKnife – which is one of the most exciting new needle-guided cancer treatments. The coverage includes the history of IRE, general technique, preclinical research, applications in clinical practice and early clinical results, and future perspectives. Contraindications, treatment planning, potential complications, follow-up imaging, and other practical aspects are fully discussed, with highlighting of useful tips and tricks.

Through the delivery of short but highly intense electrical pulses, IRE results in tumor cell membrane permeabilization, causing cells to go into apoptosis. The minimally invasive nature of IRE, combined with the prospect of completely eradicating tumors while preserving delicate structures in the ablation zone, makes IRE the object of worldwide clinical research. This book will be of value for practitioners and trainees in interventional and diagnostic radiology, surgery, medical oncology, HPB and gastroenterology, urology, and radiation oncology.

About the authors

Martijn Meijerink, MD, PhD is an interventional radiologist with interventional oncology as special field of expertise at the VU University Medical Center (VUmc) in Amsterdam, affiliated with the Cancer Center Amsterdam (CCA) which houses one of the largest academic oncology centers in Europe. He is a renowned expert in the field of interventional oncology procedures, such as radiofrequency ablation, microwave ablation, irreversible electroporation (nanoknife), transarterial bland embolization, chemo- and Y90 radioembolization. As chief of the research center for image-guided tumor ablation in Amsterdam he is continuously searching for ways to improve survival and quality of life of patients with cancer.

Hester Scheffer, MD is a senior-researcher at the VU University Medical Center in Amsterdam and one of the key opinion leaders in the field of irreversible electroporation research. Having conducted extensive translational research she was the first to prove actual cell death in the clinical setting caused by irreversible electroporation. In the preclinical setting, she focuses on electrical field modeling and the thermal component of irreversible electroporation, whereas in the clinical setting she coordinates several large trials on the efficacy of hepatic and pancreatic irreversible electroporation and she is the author of the only issued systematic review on irreversible electroporation. Together with Dr. Meijerink she is the founder of a worldwide network for irreversible electroporation research in the field of interventional oncology.

Table of contents (18 chapters)

Table of contents (18 chapters)
  • History of Image-Guided Tumor Ablation

    Pages 3-11

    Scheffer, Hester J.

  • History of Electroporation

    Pages 13-37

    Rolong, Andrea (et al.)

  • Multi-scale Biophysical Principles in Clinical Irreversible Electroporation

    Pages 41-66

    Sweeney, Daniel C. (et al.)

  • Numerical Modelling for Prediction and Evaluation of Treatment Outcome

    Pages 67-80

    Kos, Bor, PhD (et al.)

  • The Effect of Irreversible Electroporation on Blood Vessels, Bile Ducts, Urinary Tract, Intestines, and Nerves

    Pages 81-94

    Vogel, Jantien A. (et al.)

Buy this book

eBook $89.00
price for USA in USD
  • ISBN 978-3-319-55113-5
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $119.99
price for USA in USD
  • ISBN 978-3-319-55112-8
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
Softcover $119.99
price for USA in USD
  • ISBN 978-3-319-85571-4
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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Bibliographic Information

Bibliographic Information
Book Title
Irreversible Electroporation in Clinical Practice
Editors
  • Martijn Meijerink
  • Hester J. Scheffer
  • Govindarajan Narayanan
Copyright
2018
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing AG
eBook ISBN
978-3-319-55113-5
DOI
10.1007/978-3-319-55113-5
Hardcover ISBN
978-3-319-55112-8
Softcover ISBN
978-3-319-85571-4
Edition Number
1
Number of Pages
VI, 285
Number of Illustrations
17 b/w illustrations, 72 illustrations in colour
Topics