Proteomics, Metabolomics, Interactomics and Systems Biology

Proteomic Methods in Neuropsychiatric Research

Editors: Guest, Paul C. (Ed.)

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  • Presents several strategy based chapters, such as those that explain the importance of proteomics in translational medicine and the need for increased proteomic-based platforms in the drug discovery pipeline
  • Describes step-by-step instructions on how to carry out each of the protocols
  • Looks at the future of proteomic platforms including had held devices
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  • ISBN 978-3-319-52479-5
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Hardcover $199.99
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Softcover $199.99
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  • ISBN 978-3-319-84911-9
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  • Covid-19 shipping restrictions
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About this book

Due to continuous technical developments and new insights into the high complexity of neurological diseases, there is an increasing need for the application of proteomic technologies which can yield potential biomarker readouts for improved clinical management as well as for the development of new drugs by struggling pharmaceutical companies. This book describes the step-by-step use of proteomic methods such as two-dimensional gel electrophoresis, multiplex immunoassay, liquid chromatography mass spectrometry (LC-MS) and selective reaction monitoring MS, to increase our understanding of these diseases, with the ultimate aim of improving patient care.
The volume will be of high interest to clinical scientists, physicians and pharmaceutical company scientists as it gives insights into the latest technologies enabling the revolution of personalized medicine.  It is of direct interest to both technical and bench biomarker scientists as it gives step by step instructions on how to carry out each of the protocols. It is also  of interest to researchers as each technique will be presented in the context of a specific neurological disorder, including Alzheimer's disease, multiple sclerosis, autism spectrum disorders, schizophrenia, major depressive disorder and bipolar disorder. 
Finally, it will also highlight the future research efforts in this field, which are endeavoring to convert proteomic platforms to the form of hand held devices which can be used in a point of care setting and return diagnostic results within the timeframe of a visit to the general practitioner.

Table of contents (35 chapters)

Table of contents (35 chapters)
  • Application of Proteomic Techniques for Improved Stratification and Treatment of Schizophrenia Patients

    Pages 3-19

    Steiner, Johann (et al.)

  • Multiplexing Biomarker Methods, Proteomics and Considerations for Alzheimer’s Disease

    Pages 21-48

    Robinson, Renã A. S. (et al.)

  • What Have Proteomic Studies Taught Us About Novel Drug Targets in Autism?

    Pages 49-67

    Guest, Paul C. (et al.)

  • Application of Proteomic Approaches to Accelerate Drug Development for Psychiatric Disorders

    Pages 69-84

    Rahmoune, Hassan (et al.)

  • Proteomic Biomarker Identification in Cerebrospinal Fluid for Leptomeningeal Metastases with Neurological Complications

    Pages 85-96

    Galicia, Norma (et al.)

Buy this book

eBook $149.00
price for USA in USD
  • ISBN 978-3-319-52479-5
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.99
price for USA in USD
  • ISBN 978-3-319-52478-8
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
Softcover $199.99
price for USA in USD
  • ISBN 978-3-319-84911-9
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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Bibliographic Information

Bibliographic Information
Book Title
Proteomic Methods in Neuropsychiatric Research
Editors
  • Paul C. Guest
Series Title
Proteomics, Metabolomics, Interactomics and Systems Biology
Series Volume
974
Copyright
2017
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing AG
eBook ISBN
978-3-319-52479-5
DOI
10.1007/978-3-319-52479-5
Hardcover ISBN
978-3-319-52478-8
Softcover ISBN
978-3-319-84911-9
Series ISSN
2730-6216
Edition Number
1
Number of Pages
XII, 370
Number of Illustrations
10 b/w illustrations, 45 illustrations in colour
Topics