Silica-coated Magnetic Nanoparticles
An Insight into Targeted Drug Delivery and Toxicology
Authors: A. Agotegaray, Mariela, L. Lassalle, Verónica
Free Preview- Provides insights into the latest trends in nanotechnology applied to magnetic drug targeting
- Clarifies the advantages and disadvantages of using silica-coated magnetic nanoparticles for biomedical applications
- Offers an overview of the toxicological features of silica-coated magnetic nanoparticles
- Enhances understanding of the application of nanoparticles in the treatment of various diseases which constitute current biomedical challenges
Buy this book
- About this book
-
This brief offers a comprehensive discussion of magnetic targeted drug delivery of silica-coated nanodevices. Focusing on the latest trend in pharmaceutical applications of these nanodevices, a multidisciplinary overview is displayed, from synthesis and design to pharmacokenetics, biodistribution and toxicology.
Chapters include design of silica-coated magnetic nanodevices; techniques for drug loading with features applicable to biological systems; synthesis, characterization and the assessment of biomedical issues with both in vitro and in vivo experiments. Applications in the treatment of different localized diseases are also addressed in order to present the potential use of these nanosystems as global, commercially available therapeutics. - About the authors
-
1. Prof. Dr. Verónica Lassalle graduated as Bachelor in Chemistry on 2000 at the National University of South (UNS, Argentina). She obtained her PhD degree in Chemistry from Pilot Plant of Chemical Engineering (PLAPIQUI, Argentina) on 2006 in the topic “Chemical modification of SBS copolymers”. Currently, she is Senior Researcher (CONICET) and full Professor at the Chemistry Institute of South (INQUISUR), Bahía Blanca, Argentina. She participates of one Cooperation Project with Biotechnological and Genetic Engineering Centre (CIGB) from La Habana, Cuba, in the topic “Development and Research on biodrugs with antitumoral activity. A study on the delivery systems and intracellular signalization” granted by MinCyT (Argentina) and CITMA (Cuba).
2. Prof. Dr. Mariela A. Agotegaray was born in October 1982 in Bahia Blanca, Argentina. She obtained a degree in Biochemistry at the National University of the South, Bahia Blanca and at the same University she defended her doctoral thesis entitled "Coordination Complexes of Copper (II) with Fenoprofen. Chemical, Therapeutics and Toxicology”. She has developed postdoctoral studies at INQUISUR (Institute of Chemistry South), National University of the South, on "Synthesis of magnetic nanoparticles with applications in transportation and controlled release of non-steroidal anti-inflammatory drugs". She currently is Scientific Researcher for CONICET (National Council of Scientific and Technical Research) at INQUISUR, working on "Design of nanoparticles with magnetic properties and their application in the treatment of inflammatory and cardiovascular diseases”.
- Table of contents (8 chapters)
-
-
Introduction
Pages 1-8
-
Magnetic Nanoparticles as Drug Delivery Devices
Pages 9-26
-
Silica: Chemical Properties and Biological Features
Pages 27-37
-
Synthesis of Solid Silica-Coated Magnetic Nanoparticles for Drug Targeting
Pages 39-49
-
Drug Loading and Release for Specific Diseases
Pages 51-58
-
Table of contents (8 chapters)
Recommended for you
Bibliographic Information
- Bibliographic Information
-
- Book Title
- Silica-coated Magnetic Nanoparticles
- Book Subtitle
- An Insight into Targeted Drug Delivery and Toxicology
- Authors
-
- Mariela A. Agotegaray
- Verónica L. Lassalle
- Series Title
- SpringerBriefs in Molecular Science
- Copyright
- 2017
- Publisher
- Springer International Publishing
- Copyright Holder
- The Author(s)
- eBook ISBN
- 978-3-319-50158-1
- DOI
- 10.1007/978-3-319-50158-1
- Softcover ISBN
- 978-3-319-50157-4
- Series ISSN
- 2191-5407
- Edition Number
- 1
- Number of Pages
- VIII, 89
- Number of Illustrations
- 1 b/w illustrations, 25 illustrations in colour
- Topics
