Perinatal Tissue-Derived Stem Cells

1. Front Matter

   Pages i-xv

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2. Functional Dualism of Perinatal Stem Cells

   • Toshio Miki, Fabio Triolo

   Pages 1-20

3. Immunomodulatory Properties of Perinatal Tissue-Derived Mesenchymal Stem Cells

   • Seyed Mahmoud Hashemi, Sara Soudi

   Pages 21-39

4. Umbilical Cord Tissue and Wharton’s Jelly Mesenchymal Stem Cells Properties and Therapeutic Potentials

   • Erdal Karaöz, Çiğdem İnci

   Pages 41-63

5. Perinatal Tissue-Derived Endothelial Progenitor Cells

   • Abbas Shafiee, Kiarash Khosrotehrani

   Pages 65-80

6. Human Amniotic Membrane as a Biological Source for Regenerative Medicine

   • Mazaher Gholipourmalekabadi, Narendra Pal Singh Chauhan, Behrouz Farhadihosseinabad, Ali Samadikuchaksaraei

   Pages 81-105

7. Current Understanding Realities of Umbilical Cord Stem Cells Biology and Future Perspectives in Clinical Application

   • Somayeh Ebrahimi-Barough, Reza Rahbarghazi, Zohreh Bagher, Jafar Ai, Elham Hoveizi

   Pages 107-136

8. Characteristics of Mesenchymal Stem Cells Derived from Amniotic Membrane: A Potential Candidate for Stem Cell-Based Therapy

   • Somaieh Kazemnejad, Manijeh Khanmohammadi, Amir-Hassan Zarnani, Mohammad Reza Bolouri

   Pages 137-169

9. Amniotic Fluid: A Source of Stem Cells for Therapeutic Use and Modeling of Human Genetic Diseases

   • Somaieh Kazemnejad, Manijeh Khanmohammadi, Abolfazl Shirazi, Shaghayegh Arasteh, Sayeh Khanjani, Mehdi Aleahmad

   Pages 171-188

10. GMP-Compliant Perinatal Tissue-Derived Stem Cells

    • Babak Arjmand, Parisa Goodarzi, Khadijeh Falahzadeh, Hamid Reza Aghayan, Fakher Rahim, Fereshteh Mohamadi-Jahani et al.

    Pages 189-213

11. GMP Facilities for Clinical Cell Therapy Product Manufacturing: A Brief Review of Requirements and Design Considerations

    • Hamid Reza Aghayan, Babak Arjmand, Scott R. Burger

    Pages 215-227

12. Ethical Issues in Perinatal Tissue Derivation and Regenerative Medicine

    • Leila Afshar

    Pages 229-234

13. Erratum

    • Babak Arjmand

    Pages E1-E1

14. Back Matter

    Pages 235-239

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This book covers several aspects of perinatal tissue-derived stem cells, from theoretical concepts to clinical applications. Topics include functions and different sources, immunomodulatory properties, translational point of view, GMP facility design and manufacturing for clinical translation, therapeutic potentials, and finally ethical considerations. The text provides a brief review of each type of perinatal stem cells and then focuses on their multi- or pluripotent properties, regenerative capacity, and future therapeutic potential in regenerative medicine. Additionally, the book discusses GMP compliance in stem cell facilities and the manufacture of stem cells for clinical translation. The chapters are authored by world-renowned experts in the perinatal stem cell field. 
Perinatal Tissue-Derived Stem Cells: Alternative Sources of Fetal Stem Cells, part of Springer’s Stem Cell Biology and Regenerative Medicine series, is essential reading for basic and clinical scientists, clinicians, and pharmaceutical experts working or conducting research in the fields of stem cell biology, molecular aspects of stem cell research, tissue engineering, regenerative medicine, and cellular therapy.




 


 

• amniotic cells
• cellular therapy
• extra-embryonic
• placenta
• perinatal cells

• Endocrinology and Metabolism Research Center Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences & Brain and Spinal Cord Injury Research Center Tehran University of Medical Sciences, Tehran, Iran

  Babak Arjmand

Dr. Babak Arjmand received his M.D. from Iran University of Medical Sciences, and Ph.D. from Tehran University of Medical Sciences, Tehran, Iran. He is currently vice chancellor for research at Metabolic Disorders Research Center, Endocrinology and Metabolism Cellular-Molecular Sciences Institute in Tehran, Iran. His research focuses on the stem cell translation from the basic to the clinic and GMP-compliant manufacturing for cellular therapy. Dr. Arjmand is member of different cell and tissue committees and groups such as National Committee of Tissue, Cell and Gene Therapy at Iran Food and Drug Organization (MOH), Iranian Council of Stem Cell Technologies, National Working Group for providing National Guideline on Stem Cell therapy, etc.

Policies and ethics