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The Immune Response to Implanted Materials and Devices

The Impact of the Immune System on the Success of an Implant

Editors: Corradetti, Bruna (Ed.)

  • Explores the detrimental and beneficial effects of immune cells' activation in response to implants
  • Highlights the possibilities of biomimicry in modulating immune reactions
  • Describes the latest approaches to the activation of cellular immunity
  • Discusses regulatory challenges, translational considerations and literature case studies pertinent to the immunological safety of nanotechnology-based devices>
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Buy this book

eBook $99.00
price for USA in USD (gross)
  • ISBN 978-3-319-45433-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $159.99
price for USA in USD
  • ISBN 978-3-319-45431-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $129.00
price for USA in USD
  • ISBN 978-3-319-83293-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book provides a comprehensive overview of the cascade of events activated in the body following the implant of biomaterials and devices. It is one of the first books to shed light on the role of the host immune response on therapeutic efficacy, and reviews the state-of-the-art for both basic science and medical applications. The text examines advantages and disadvantages of the use of synthetic versus natural biomaterials. Particular emphasis is placed on the role of biomimicry in the development of smart strategies able to modulate infiltrating immune cells, thus reducing side effects (such as acute and chronic inflammation, fibrosis and/or implant rejection) and improving the therapeutic outcome (healing, tissue restoration). Current cutting-edge approaches in tissue engineering, regenerative medicine, and nanomedicine offer the latest insights into the role immunomodulation in improving tolerance during tissue transplant in the treatment of orthopaedic, pancreatic, and hepatic diseases. "Immune Response to Implanted Materials and Devices" is intended for an audience of graduate students and professional researchers in both academia and industry interested in the development of smart strategies, which are able to exploit the self-healing properties of the body and achieve functional tissue restoration.

Table of contents (12 chapters)

  • Host Response to Implanted Materials and Devices: An Overview

    Scarritt, Michelle E. (et al.)

    Pages 1-14

  • Implications of the Acute and Chronic Inflammatory Response and the Foreign Body Reaction to the Immune Response of Implanted Biomaterials

    Anderson, James M. (et al.)

    Pages 15-36

  • Macrophages: The Bad, the Ugly, and the Good in the Inflammatory Response to Biomaterials

    Scatena, Marta (et al.)

    Pages 37-62

  • Understanding Nanoparticle Immunotoxicity to Develop Safe Medical Devices

    Dobrovolskaia, Marina A.

    Pages 63-80

  • Host Response to Synthetic Versus Natural Biomaterials

    Sarkar, Kishor (et al.)

    Pages 81-105

Buy this book

eBook $99.00
price for USA in USD (gross)
  • ISBN 978-3-319-45433-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $159.99
price for USA in USD
  • ISBN 978-3-319-45431-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $129.00
price for USA in USD
  • ISBN 978-3-319-83293-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
The Immune Response to Implanted Materials and Devices
Book Subtitle
The Impact of the Immune System on the Success of an Implant
Editors
  • Bruna Corradetti
Copyright
2017
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing Switzerland
eBook ISBN
978-3-319-45433-7
DOI
10.1007/978-3-319-45433-7
Hardcover ISBN
978-3-319-45431-3
Softcover ISBN
978-3-319-83293-7
Edition Number
1
Number of Pages
XVIII, 241
Number of Illustrations
5 b/w illustrations, 20 illustrations in colour
Topics