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Malaria

Immune Response to Infection and Vaccination

  • Book
  • © 2017

Overview

Editors:
  1. Maria M. Mota

    1. Instituto de Medicina Molecular, Faculdade de Medicina Universidade de Lisboa, Lisbon, Portugal

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  2. Ana Rodriguez

    1. Division of Parasitology, Department of Microbiology, New York University School of Medicine, New York, USA

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    You can also search for this editor in PubMed   Google Scholar

  • Contributed by top research leaders in the field

  • Compares the immune responses to both malaria infection and malaria vaccines, which are traditionally treated separately

  • Covers the immune responses to the different stages of malaria

  • Includes supplementary material: sn.pub/extras

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-vi
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  2. Immune Response to Infection

    1. Front Matter

      Pages 1-1
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    2. Innate Immunity to Malaria

      • Anton Götz, Maureen Ty, Angelo Ferreira Chora, Vanessa Zuzarte-Luís, Maria M. Mota, Ana Rodriguez
      Pages 3-25

    3. Mechanisms of Adaptive Immunity to Plasmodium Liver-Stage Infection: The Known and Unknown

      • Stina L. Urban, Katherine L. Doll, John T. Harty
      Pages 27-45

    4. Adaptive Immunity to Plasmodium Blood Stages

      • Michelle N. Wykes, Robin Stephens, Ian A. Cockburn
      Pages 47-66

    5. Pathogenetic Immune Responses in Cerebral Malaria

      • Georges Emile Raymond Grau, Samuel Crocodile Wassmer
      Pages 67-80

    6. A Role for Autoimmunity in the Immune Response Against Malaria

      • Juan Rivera-Correa, Ana Rodriguez
      Pages 81-95

  3. Immune Response to Malaria Vaccines: Liver Stage Vaccines

    1. Front Matter

      Pages 97-97
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    2. Whole-Sporozoite Malaria Vaccines

      • António M. Mendes, Anja Scholzen, Ann-Kristin Mueller, Shahid M. Khan, Robert W. Sauerwein, Miguel Prudêncio
      Pages 99-137

    3. Immune Responses to the RTS,S/AS01 Malaria Vaccine Candidate: Lessons from Human Immunology, Parasitologic and Clinical Evaluations

      • Johan Vekemans
      Pages 139-156

    4. Viral Vector Vaccines for Liver-Stage Malaria

      • Cristina Fernández-Arias, Moriya Tsuji
      Pages 157-169

    5. Epitopic Malaria Vaccines Comprised of Minimal T- and B-Cell Epitopes of the P. falciparum CS Protein

      • Elizabeth H. Nardin
      Pages 171-194

  4. Immune Response to Malaria Vaccines: Blood Stage Vaccines

    1. Front Matter

      Pages 195-195
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    2. Immune Responses to Whole-Organism Blood-Stage Malaria Vaccines

      • Amber I. Raja, Danielle I. Stanisic, Michael F. Good
      Pages 197-210

    3. Subunit Blood-Stage Malaria Vaccines

      • Alexander D. Douglas
      Pages 211-238

  5. Immune Response to Malaria Vaccines: Transmission Blocking Vaccines

    1. Front Matter

      Pages 239-239
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    2. Antimalarial Transmission-Blocking Vaccines

      • R. E. Sinden, Sumi Biswas, A. M. Blagborough
      Pages 241-272

  6. Back Matter

    Pages 273-278
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Keywords

About this book

Currently, malaria kills more than 300,000 people per year, making it a top priority of world leaders and international organizations, who are working towards implementing and coordinating efforts to eradicate this disease. An effective malaria vaccine is recognized as the key element that will decide between success and failure in this fight. At present, despite intensive research efforts, such a vaccine is not yet available for use. However, there are a number of advanced candidate vaccines with high chances of success in the short term. 

Malaria: Immune Response to Infection and Vaccination provides a comprehensive view on the immune response to malaria and to the different vaccines under development. The book offers the following:

- Contributions by top research leaders in the field,

- Comparisons of the immune responses to both malaria infection and malaria vaccines, which are traditionally treated separately,  

- Coverage of the immune responses to the different stages of malaria, which are frequently treated as separate fields of research.

  

Reviews

“This book will be an excellent resource for established malaria investigators interested in a broad look at the overall malaria vaccine effort. As well, the book will provide an excellent opportunity for new investigators entering the malaria field, including students and fellows, to quickly establish a relevant base of knowledge. … The authors deliver a well-written, excellent review of the state of the field that integrates basic studies of immune responses with applied aspects of vaccine development.” (James M. Burns, Doody's Book Reviews, May, 2017)

Editors and Affiliations

  • Instituto de Medicina Molecular, Faculdade de Medicina Universidade de Lisboa, Lisbon, Portugal

    Maria M. Mota

  • Division of Parasitology, Department of Microbiology, New York University School of Medicine, New York, USA

    Ana Rodriguez

About the editors

Maria M. Mota, Instituto de Medicina Molecular, Lisbon, Portugal 

Ana Rodriguez, New York University School of Medicine, Department of Microbiology, New York, USA

Bibliographic Information

  • Book Title: Malaria

  • Book Subtitle: Immune Response to Infection and Vaccination

  • Editors: Maria M. Mota, Ana Rodriguez

  • DOI: https://doi.org/10.1007/978-3-319-45210-4

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing Switzerland 2017

  • Hardcover ISBN: 978-3-319-45208-1Published: 19 January 2017

  • Softcover ISBN: 978-3-319-83239-5Published: 30 April 2018

  • eBook ISBN: 978-3-319-45210-4Published: 12 January 2017

  • Edition Number: 1

  • Number of Pages: VI, 278

  • Number of Illustrations: 3 b/w illustrations, 10 illustrations in colour

  • Topics: Immunology, Vaccine, Infectious Diseases

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