Regenerative Strategies for the Treatment of Knee Joint Disabilities

1. Front Matter

   Pages i-ix

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2. Articular Cartilage Lesions: Clinical Management and Regenerative Strategies

   1. Front Matter

      Pages 1-1

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   2. Knee Articular Cartilage

      • Marta Ondrésik, Joaquim Miguel Oliveira, Rui Luís Reis

      Pages 3-20

   3. Synovial Knee Joint

      • Isabel Oliveira, Cristiana Gonçalves, Rui Luís Reis, Joaquim Miguel Oliveira

      Pages 21-28

   4. Clinical Management of Articular Cartilage Lesions

      • Carlos A. Vilela, Cristina Correia, Joaquim Miguel Oliveira, Rui Amandi Sousa, Rui Luís Reis, João Espregueira-Mendes

      Pages 29-53

   5. Osteoarthritis

      • Marta Ondrésik, Joaquim Miguel Oliveira, Rui Luís Reis

      Pages 55-72

   6. Cartilage Tissue Engineering and Regenerative Strategies

      • Alain da Silva Morais, Joaquim Miguel Oliveira, Rui Luís Reis

      Pages 73-96

   7. Advances in Biomaterials for the Treatment of Articular Cartilage Defects

      • Cristiana Gonçalves, Hajer Radhouani, Joaquim Miguel Oliveira, Rui Luís Reis

      Pages 97-126

3. Osteochondral Lesions of the Knee: From Repair towards Regeneration

   1. Front Matter

      Pages 127-127

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   2. Fundamentals on Osteochondral Tissue Engineering

      • Viviana Ribeiro, Sandra Pina, Joaquim Miguel Oliveira, Rui Luís Reis

      Pages 129-146

   3. Pre-clinical and Clinical Management of Osteochondral Lesions

      • Sandra Pina, Viviana Ribeiro, Joaquim Miguel Oliveira, Rui Luís Reis

      Pages 147-161

   4. Rapid Prototyping for the Engineering of Osteochondral Tissues

      • Alessandra Marrella, Marta Cavo, Silvia Scaglione

      Pages 163-185

   5. Biomimetic Approaches for the Engineering of Osteochondral Tissues

      • Le-Ping Yan

      Pages 187-211

   6. Osteochondral Tissue Engineering and Regenerative Strategies

      • Raphaël F. Canadas, Alexandra P. Marques, Rui Luís Reis, Joaquim Miguel Oliveira

      Pages 213-233

4. Meniscus Injuries: Replacement, Repair and Regeneration

   1. Front Matter

      Pages 235-235

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   2. Basics of the Meniscus

      • Ibrahim Fatih Cengiz, Joana Silva-Correia, Helder Pereira, João Espregueira-Mendes, Joaquim Miguel Oliveira, Rui Luís Reis

      Pages 237-247

   3. Biomaterials in Meniscus Tissue Engineering

      • João B. Costa, Joaquim Miguel Oliveira, Rui Luís Reis

      Pages 249-270

   4. Advanced Regenerative Strategies for Human Knee Meniscus

      • Ibrahim Fatih Cengiz, Joana Silva-Correia, Helder Pereira, João Espregueira-Mendes, Joaquim Miguel Oliveira, Rui Luís Reis

      Pages 271-285

5. Knee Ligament Injuries

   1. Front Matter

      Pages 287-287

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   2. Fundamentals on Injuries of Knee Ligaments in Footballers

      • Hélder Pereira, Sérgio Gomes, Luís Silva, António Cunha, Joaquim Miguel Oliveira, Rui Luís Reis et al.

      Pages 289-321

This book presents regenerative strategies for the treatment of knee joint disabilities. The book  is composed of four main sections totaling 19 chapters which review the current knowledge on the clinical management and preclinical regenerative strategies. It examines the role of different natural-based biomaterials as scaffolds and implants for addressing different tissue lesions in the knee joint. Section one provides an updated and comprehensive discussion on articular cartilage tissue regeneration. Section two focuses on the important contributions for bone and osteochondral tissue engineering. Section three overview the recent advances on meniscus repair/regeneration strategies. Finally, section four further discusses the current strategies for treatment of ligament lesions. Each chapter is prepared by world know expert on their fields, so we do firmly believe that the proposed book will be a reference in the area of biomaterials for regenerative medicine.

• 3B's Research Group
• Articular Cartilage Tissue Regeneration
• Biodegradables
• Ligament Lesions
• Meniscus Regeneration
• Meniscus Repair
• Osteochondral Tissue Engineering
• Starch- and Gellan Gum-based Materials

• 3B’s Research Group—Biomaterials, Biodegradables and Biomimetics, University of Minho, Guimarães, Portugal

  Joaquim Miguel Oliveira

• ICVS/3B’s—PT Government Associate, Laboratory, University of Minho, Guimarães, Portugal

  Rui Luís Reis

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