The Role of Pendrin in Health and Disease

Molecular and Functional Aspects of the SLC26A4 Anion Exchanger

Editors: Dossena, Silvia, Paulmichl, Markus (Eds.)

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  • Written by experts in pendrin research
  • Provides readers with detailed knowledge about pendrin genetics, structure and pharmacology
  • Helps in understanding the molecular mechanisms of pendrin related disorders
  • Combines in the best way cutting-edge research with clinical aspects of pendrin function
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Buy this book

eBook $149.00
price for USA in USD (gross)
  • ISBN 978-3-319-43287-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.99
price for USA in USD
  • ISBN 978-3-319-43285-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $199.99
price for USA in USD
  • ISBN 978-3-319-82780-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book reviews the current state of knowledge on the genetics, molecular biology and physiology of pendrin, with a particular focus on pendrin dysfunction and the consequences for human health. 


Pendrin is a membrane transport protein expressed in the thyroid, inner ear, kidney and airways, and was recently found in a variety of other tissues and organs. Pendrin malfunction may cause a genetic disease called Pendred syndrome or non-syndromic deafness.


The book provides a thorough description of the multifaceted role of pendrin in human health and disease. As such, it offers an invaluable tool for physiology and pathology researchers, while also providing essential guidance for otorhinolaryngologists and endocrinologists in the diagnosis of Pendred syndrome and pendrin-related deafness.

About the authors

Prof. Dr. Markus Paulmichl Institute of Pharmacology and Toxicology of the Paracelsus Medical University Salzburg, Austria
Silvia Dossena, PhD Institute of Pharmacology and Toxicology of the Paracelsus Medical University Salzburg, Austria

Reviews

“The purpose is to summarize the current knowledge about the role of pendrin in normal physiology and disease pathology. The intended audience is predominantly researchers and physicians interested in a detailed description of the multifaceted function of pendrin. However, the book also could serve as a good source for undergraduate and graduate students and postgraduate trainees interested in thyroid physiology and pathology as well as physiology, pathology, and diagnosis of deafness in general.” (Partha Kasturi, Doody’s Book Reviews, June, 2017) 


Table of contents (11 chapters)

Table of contents (11 chapters)

Buy this book

eBook $149.00
price for USA in USD (gross)
  • ISBN 978-3-319-43287-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.99
price for USA in USD
  • ISBN 978-3-319-43285-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $199.99
price for USA in USD
  • ISBN 978-3-319-82780-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
The Role of Pendrin in Health and Disease
Book Subtitle
Molecular and Functional Aspects of the SLC26A4 Anion Exchanger
Editors
  • Silvia Dossena
  • Markus Paulmichl
Copyright
2017
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing Switzerland
eBook ISBN
978-3-319-43287-8
DOI
10.1007/978-3-319-43287-8
Hardcover ISBN
978-3-319-43285-4
Softcover ISBN
978-3-319-82780-3
Edition Number
1
Number of Pages
X, 226
Number of Illustrations
10 b/w illustrations, 26 illustrations in colour
Topics