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  • © 2019

In Vitro Fertilization

A Textbook of Current and Emerging Methods and Devices

  • A revised and expanded second edition of the 2012 textbook covering all aspects of in vitro fertilization, including over 20 new chapters
  • Arranged thematically in sections, with new summary key points and review questions in each chapter
  • An excellent learning resource for reproductive endocrinologists, urologists, embryologists, biologists and infertility researchers in training

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eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

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Table of contents (79 chapters)

  1. Front Matter

    Pages I-XXII
  2. Journey of Human Gametes In Vitro: 1978 to 2018

    • Yuval Or, Shir Dar, Zeev Shoham
    Pages 1-6
  3. Setting Up an ART Unit: Planning, Design and Organization

    1. Front Matter

      Pages 7-7
    2. Setting Up an ART Unit: Planning, Design, and Construction

      • Jacques Cohen, Mina Alikani, Antonia Gilligan, Tim Schimmel
      Pages 9-19
    3. Building the Laboratory

      • Dean E. Morbeck, Marlena Duke
      Pages 21-27
    4. Air Quality Management

      • Johan Guns, Ronny Janssens
      Pages 29-37
    5. Risk and Safety in the IVF Clinic

      • Julius Hreinsson, Kia Borg
      Pages 47-55
    6. Control of Variables

      • Cecilia Sjoblom, Georgios Liperis
      Pages 57-68
  4. IVF Laboratory Equipment and Culture Systems

    1. Front Matter

      Pages 77-77
    2. Essential Instruments and Disposable Supplies for an IVF Laboratory

      • Leslie Weikert, Christa Mackenzie, Klaus E. Wiemer
      Pages 79-84
    3. CO2 and Low-O2 Incubators

      • Marius Meintjes
      Pages 85-94
  5. Oocyte Preparation for IVF/ICSI

    1. Front Matter

      Pages 121-121
    2. Assessment of Oocyte Quality

      • Basak Balaban
      Pages 123-132
    3. Oocyte Denuding

      • Laura Francesca Rienzi, Roberta Maggiulli, Filippo Maria Ubaldi
      Pages 133-145
  6. Embryo Culture Methods

    1. Front Matter

      Pages 147-147

About this book

Now in its revised and expanded second edition - including over 20 new chapters - this comprehensive textbook remains a unique and accessible description of the current and developing diagnostic and treatment techniques and technologies comprising in vitro fertilization (IVF). Arranged thematically in sections, each chapter covers a key topic in IVF in a sensible presentation. Parts one and two describe the planning, design and organization of an ART unit and IVF laboratory and equipment and systems, respectively. The sections that follow provide detailed descriptions of IVF techniques, embryo culture methods, sperm processing and selection, insemination procedures, micromanipulation, embryo evaluation, cryopreservation, and embryo transfer. Concluding sections address issues of management and regulation of ART labs across the globe, as well as special topics and emerging techniques and devices. Chapter authors, all experts in the field, contribute their expertise from around the world.

With the addition of learning key points and review questions at the beginning and end of each chapter, this new edition of In Vitro Fertilization is a readily accessible, high quality instructional resource for reproductive medicine trainees at all levels. Practicing reproductive endocrinologists, urologists, and embryologists also will find value in the book, as will infertility researchers.

Editors and Affiliations

  • Reproductive Biology Associates – Prelude, Atlanta, USA

    Zsolt Peter Nagy

  • Astra Fertility Group, Mississauga, Canada

    Alex C. Varghese

  • Cleveland Clinic, Cleveland, USA

    Ashok Agarwal

About the editors

Zsolt Peter Nagy, MD, PhD

Scientific Director

Reproductive Biology Associates – Prelude

Atlanta, GA, USA


Alex C Varghese, PhD

Scientific Director

Astra Fertility Group

Mississauga, ON, Canada



Ashok Agarwal, PhD, HCLD (ABB), EMB (ACE),

American Center for Reproductive Medicine

Cleveland Clinic

Cleveland, OH, USA



Bibliographic Information

  • Book Title: In Vitro Fertilization

  • Book Subtitle: A Textbook of Current and Emerging Methods and Devices

  • Editors: Zsolt Peter Nagy, Alex C. Varghese, Ashok Agarwal

  • DOI: https://doi.org/10.1007/978-3-319-43011-9

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Switzerland AG 2019

  • Hardcover ISBN: 978-3-319-43010-2Published: 19 July 2019

  • eBook ISBN: 978-3-319-43011-9Published: 03 July 2019

  • Edition Number: 2

  • Number of Pages: XXII, 962

  • Number of Illustrations: 15 b/w illustrations, 198 illustrations in colour

  • Topics: Reproductive Medicine, Endocrinology

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access