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Adipocytokines, Energy Balance, and Cancer

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  • © 2017

Overview

  • Analyzes the components and molecular biology of adipose tissue and differences in activities and interactions related to its body distribution
  • Explores both the physiologic and pathologic functions of the major adipocytokines, including their regulatory role and their role in cancer etiology, promotion, and progression
  • Discusses IL-6 signaling pathways and leptin signaling pathways as therapeutic targets

Part of the book series: Energy Balance and Cancer (EBAC, volume 12)

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Table of contents (11 chapters)

Keywords

About this book

Adipocytokines provide the circuitry by which adipose tissue communicates among its component cells which include adipocytes, stromal cells, immune cells and vascular elements, with adipose tissue depots in other locations throughout the body and with other tissues in order to regulate physiologic processes of energy intake, utilization, and distribution. Since disturbances, both qualitative and quantitative, in adipocytokine function contribute significantly to many of the comorbidities associated with obesity, including diabetes, cardiovascular disease and cancer, this volume, which discusses most of the major adipocytokines independently and collectively and their roles in normal and pathologic processes, should be useful to all individuals seeking a deeper understanding of these processes. Moreover, it provides a valuable complement to the series on Energy Balance and Cancer, in which each volume is focused on a specific aspect of this process, which now constitutesan expanding problem as the obesity pandemic continues and more of the population reaches the age where cancer is most prevalent. This volume should provide a valuable resource to all clinicians and scientists engaged in caring for susceptible patients and in exploring the relation between energy balance and cancer as well as an important platform to providing the background for research development.

Editors and Affiliations

  • Department of Cellular and Molecular Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, USA

    Ofer Reizes

  • Center for Science, Health and Society, Case Western Reserve University, Cleveland, USA

    Nathan A. Berger

About the editors

Nathan A. Berger, MD, is Distinguished University Professor, Hanna-Payne Professor of Experimental Medicine, Professor Medicine, Biochemistry and Oncology, Director, Center for Science, Health, and Society, Case Western Reserve University, School of Medicine.

Bibliographic Information

  • Book Title: Adipocytokines, Energy Balance, and Cancer

  • Editors: Ofer Reizes, Nathan A. Berger

  • Series Title: Energy Balance and Cancer

  • DOI: https://doi.org/10.1007/978-3-319-41677-9

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing Switzerland 2017

  • Hardcover ISBN: 978-3-319-41675-5Published: 10 November 2016

  • Softcover ISBN: 978-3-319-82408-6Published: 27 June 2018

  • eBook ISBN: 978-3-319-41677-9Published: 31 October 2016

  • Series ISSN: 2199-2622

  • Series E-ISSN: 2199-2630

  • Edition Number: 1

  • Number of Pages: XII, 302

  • Number of Illustrations: 3 b/w illustrations, 16 illustrations in colour

  • Topics: Cancer Research

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