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  • © 2016

Epigenetics in Cardiac Disease

  • The first book dedicated to epigenetic regulation in cardiac diseases
  • Provides insight into the complexity of histon and DNA modifications that contribute to cardiac development and the pathogenesis of cardiac diseases
  • Offers a broad overview on the topic and discusses the latest advances in the field

Part of the book series: Cardiac and Vascular Biology (Abbreviated title: Card. vasc. biol., volume 1)

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Softcover Book USD 169.99
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Hardcover Book USD 169.99
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Table of contents (14 chapters)

  1. Front Matter

    Pages i-viii
  2. Epigenetics: Chromatin Organization and Function

    • Genevieve P. Delcuve, Dilshad H. Khan, Vichithra R. B. Liyanage, Sanzida Jahan, Mojgan Rastegar, Lorrie A. Kirshenbaum et al.
    Pages 1-35
  3. Epigenetic Regulations in Cardiac Development

    • Mei Xin, Kunhua Song
    Pages 53-73
  4. DNA Methylation in Heart Failure

    • Justus Stenzig, Roger S-Y Foo
    Pages 75-102
  5. Chromatin Remodeling in Heart Failure

    • Pei Han, Jin Yang, Ching Shang, Ching-Pin Chang
    Pages 103-124
  6. The Lysine Acetyltransferases in Cardiovascular Disease

    • Nanette H. Bishopric
    Pages 147-190
  7. HDAC Signaling Networks in Heart Failure

    • Mariya Kronlage, Hugo A. Katus, Johannes Backs
    Pages 191-208
  8. Epigenetic and Nongenomic Roles for Histone Deacetylases in Heart Failure

    • Weston W. Blakeslee, Philip D. Tatman, Timothy A. McKinsey
    Pages 209-229
  9. Sirtuins as Regulators of Cardiac Hypertrophy and Heart Failure

    • Sadhana Samant, Mahesh P. Gupta
    Pages 263-282
  10. BET Bromodomains and P-TEFb in Cardiac Transcription and Heart Failure Pathogenesis

    • Priti Anand, Amir Munir, Saptarsi M. Haldar
    Pages 283-296
  11. Long Noncoding RNAs in Heart Disease

    • Constantin Kühl, Norbert Frey
    Pages 297-316
  12. Correction to: Epigenetics in Cardiac Disease

    • Johannes Backs, Timothy A. McKinsey
    Pages C1-C1

About this book

This book describes important advances in our understanding of how environmental conditions affect cardiac gene expression through epigenetic mechanisms. Further, it discusses the roles of chromatin modifications (in particular DNA methylation and histone modifications) and of chromatin regulators in the context of cardiac diseases. The book provides readers with an overview of our current understanding of epigenetic regulation in the heart, and will stimulate further research in this exciting field. Edited and written by internationally respected experts, it addresses the needs of professors, students and researchers working in the fields of cardiac biology and epigenetics.

Editors and Affiliations

  • Department of Molecular, Cardiology and Epigenetics, University of Heidelberg, Heidelberg, Germany

    Johannes Backs

  • Department of Medicine, Division of Cardiology, University of Colorado Denver, Aurora, USA

    Timothy A. McKinsey

About the editors

Prof. Johannes Backs, MD Research Unit Cardiac Epigenetics University of Heidelberg Im Neuenheimer Feld 410 69221 Heidelberg Germany johannes.backs@med.uni-heidelberg.de

Prof. Timothy A. McKinsey, PhD Department of Medicine/Division of Cardiology University of Colorado Denver 12700 E 19th Avenue Aurora CO 80045 USA timothy.mckinsey@ucdenver.edu

Bibliographic Information

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access