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Selenium

Its Molecular Biology and Role in Human Health

Editors: Hatfield, D.L., Schweizer, U., Tsuji, P.A., Gladyshev, V.N. (Eds.)

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  • Provides an overview of the health benefits of Selenium
  • Brings the research on selenium up-to-date
  • Provides an in depth reference for those entering the selenium field
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eBook $189.00
price for USA in USD (gross)
  • ISBN 978-3-319-41283-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.99
price for USA in USD
  • ISBN 978-3-319-41281-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $249.99
price for USA in USD
  • ISBN 978-3-319-82313-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

In the current edition, Selenium: Its Molecular Biology and Role in Human Health expands extensively on the previous editions providing readers with the most significant advances in the rapidly developing selenium field. Evidence from epidemiology and veterinary science supports the essential role of selenium in (human) health, but its split personality in both preventing and supporting cancer and also in promoting insulin resistance has become more clearly defined. The pivotal role of glutathione peroxidase 4 in a new process of programmed cell death, ferroptosis, brings new impetus to the field. Recently defined mutations in selenoprotein and biosynthesis factor genes have been identified in patients, and the resulting disorders further emphasize the significance of selenoproteins in human health. The mechanism of selenoprotein biosynthesis, the functions of selenoproteins, and the roles of dietary selenium have been further elucidated, and new regulatory mechanisms involving selenoproteins discovered. The book, therefore, covers the breadth of current selenium research. With up-to-date chapters written by leaders in their fields, it serves as an invaluable resource for novices as well as specialists.

About the authors

Dolph Hatfield is Scientist Emeritus in the Molecular Biology of Selenium Section at the National Cancer Institute.

Ulrich Schweizer, is Professor at the Institute of Biochemistry and Molecular Biology, Rheinische Friedrich-Wilhelms-Universität Bonn.

Petra Tsuji is Assistant Professor in the at the Department of Biological Sciences at Towson University.

Vadim N. Gladyshev, is Professor in the Division of Genetics, Department of Medicine at the Brigham and Women’s Hospital and Harvard Medical School.


Reviews

“The book provides up to date and comprehensive review of hot topics in the field of Se research and is the source of valuable information for people working in science, clinics and industry.” (Jela Brozmanova, Neoplasma, Vol. 64 (3), 2017)


Table of contents (50 chapters)

Table of contents (50 chapters)
  • Selenocysteine tRNA[Ser]Sec: From Nonsense Suppressor tRNA to the Quintessential Constituent in Selenoprotein Biosynthesis

    Pages 3-12

    Carlson, Bradley A. (et al.)

  • Eukaryotic Mechanisms of Selenocysteine Incorporation and Its Reconstitution In Vitro

    Pages 13-24

    Pinkerton, Mark H. (et al.)

  • Probing Selenoprotein Translation by Ribosome Profiling

    Pages 25-37

    Howard, Michael T.

  • Pathways in De Novo Biosynthesis of Selenocysteine and Cysteine in Eukaryotes

    Pages 39-45

    Gladyshev, Vadim N. (et al.)

  • Prokaryotic Selenoprotein Biosynthesis and Function

    Pages 47-58

    Rother, Michael

Buy this book

eBook $189.00
price for USA in USD (gross)
  • ISBN 978-3-319-41283-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.99
price for USA in USD
  • ISBN 978-3-319-41281-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $249.99
price for USA in USD
  • ISBN 978-3-319-82313-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Selenium
Book Subtitle
Its Molecular Biology and Role in Human Health
Editors
  • Dolph L. Hatfield
  • Ulrich Schweizer
  • Petra A. Tsuji
  • Vadim N. Gladyshev
Copyright
2016
Publisher
Springer International Publishing
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-3-319-41283-2
DOI
10.1007/978-3-319-41283-2
Hardcover ISBN
978-3-319-41281-8
Softcover ISBN
978-3-319-82313-3
Edition Number
4
Number of Pages
XXXI, 628
Number of Illustrations
29 b/w illustrations, 59 illustrations in colour
Topics