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The Functional Nucleus

Editors: Bazett-Jones, David J., Dellaire, Graham (Eds.)

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  • Provides a state-of-the-art review on nuclear structure and functions Highlights the relation between epigenomics and nuclear architecture
  • Gives an outlook on possible medical applications
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eBook $219.00
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  • ISBN 978-3-319-38882-3
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  • ISBN 978-3-319-81768-2
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About this book

This book gives an in-depth overview on nuclear structure and function. It clearly shows that the epigenome and the three-dimensional organization of the nucleus are not independent properties. The intimate relationship between the location and the epigenetic modifications of gene loci is highlighted. Finally, it shows that the complex three-dimensional organization of the nucleus is not just of academic interest: The structure, composition and function of virtually all of the sub-nuclear compartments identified so far can be implicated to a list of human genetic diseases. Hence, a detailed elucidation of how these domains are assembled and function will provide new opportunities for therapeutic intervention in clinical practice.

About the authors

David P. Bazett-JonesThe Hospital for Sick Children, Toronto, ON, Canada 
                Graham DellaireDalhousie University, Halifax, NS, Canada

Table of contents (21 chapters)

Table of contents (21 chapters)

Buy this book

eBook $219.00
price for USA in USD (gross)
  • ISBN 978-3-319-38882-3
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.99
price for USA in USD
  • ISBN 978-3-319-38880-9
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
Softcover $279.99
price for USA in USD
  • ISBN 978-3-319-81768-2
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
The Functional Nucleus
Editors
  • David J. Bazett-Jones
  • Graham Dellaire
Copyright
2016
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing Switzerland
eBook ISBN
978-3-319-38882-3
DOI
10.1007/978-3-319-38882-3
Hardcover ISBN
978-3-319-38880-9
Softcover ISBN
978-3-319-81768-2
Edition Number
1
Number of Pages
VI, 513
Number of Illustrations
8 b/w illustrations, 48 illustrations in colour
Topics

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