Early Nutrition and Lifestyle Factors

1. Front Matter

   Pages i-x

   PDF

2. Placentation as a Predictor of Feto-Placental Outcome: Effects of Early Nutrition

   • Asim K. Duttaroy, Sanjay Basak

   Pages 1-12

3. Early Placentation Processes

   • Asim K. Duttaroy, Sanjay Basak

   Pages 13-21

4. Glucose and Amino Acid and Their Roles in Placentation

   • Asim K. Duttaroy, Sanjay Basak

   Pages 23-38

5. Dietary Fatty Acids and Placentation

   • Asim K. Duttaroy, Sanjay Basak

   Pages 39-50

6. B Vitamins and Their Role on Trophoblast Growth and Development

   • Asim K. Duttaroy, Sanjay Basak

   Pages 51-68

7. Fat-Soluble and Antioxidant Vitamins and Minerals: Their Roles in Placentation

   • Asim K. Duttaroy, Sanjay Basak

   Pages 69-89

8. Endocrine Factors and Their Effects on Placentation

   • Asim K. Duttaroy, Sanjay Basak

   Pages 91-100

9. Maternal Lifestyle Factors and Placentation

   • Asim K. Duttaroy, Sanjay Basak

   Pages 101-118

10. Regulation of Placentation by Environmental Factors

    • Asim K. Duttaroy, Sanjay Basak

    Pages 119-128

11. Placental Epigenetics and Its Importance in Placental Development

    • Asim K. Duttaroy, Sanjay Basak

    Pages 129-137

12. Gene Regulation, microRNA, and Placentation

    • Asim K. Duttaroy, Sanjay Basak

    Pages 139-149

13. Sources of Key Nutrients for Successful Placentation

    • Asim K. Duttaroy, Sanjay Basak

    Pages 151-159

This book highlights the impact of nutrients on early placentation processes and their relevance for fetal growth and pregnancy outcome.​ The role of maternal nutrition on fetal growth and development has been evidenced in many epidemiological studies that included infamous Dutch famine, Helsinki Birth cohort and others. Fetal programming hypothesis states that the nutritional and other environmental conditions under which an individual develops from pre-conception to birth has a major impact on the future health of the newborn child. The developmental environment of the fetus is primarily dependent on two major factors that are maternal nutritional state (excess/low/imbalance) and placental function. Placentation is characterized by the extensive remodeling of the maternal uterine vasculature producing low-resistance blood vessels that facilitate the exchange of nutrients and wastes between the mother and the fetus. Cellular and molecular mechanisms involved in human placental blood vessel formation, which are now well established, are discussed.

• Placentation
• Nutrition
• Intrauterine growth
• Trophoblast
• Angiogenic signaling
• Preeclampsia
• Blastocyst
• Early pregnancy
• Feto-placental unit
• Folic acid
• Vitamin supplementation
• Implantation
• Endometrium
• Placental epigenetics
• Lifestyle Factors

• Dept of Nutrition, University of Oslo Dept of Nutrition, Oslo, Norway

  Asim K. Duttaroy

• National Institute of Nutrition, Indian Council of Medical Research , Hyderabad, India

  Sanjay Basak

Asim K. Duttaroy is Professor in the Division of Clinical Nutrition at the University of Oslo, Norway. Sanjay Basak, PhD, works in the Molecular Biology Division of the National Institute of Nutrition (ICMR), Hyderabad, India.

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