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Alzheimer’s Turning Point

A Vascular Approach to Clinical Prevention

  • Provides an overview of the available technology for early detection and therapeutic management of risk factors to Alzheimer’s before severe cognitive impairment symptoms appear

  • Offers an in-depth examination of various hypotheses and current treatments

  • A compelling read for professionals, students and for those looking to learn more about this disorder

  • Includes supplementary material: sn.pub/extras

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Table of contents (20 chapters)

  1. Front Matter

    Pages i-xvi
  2. How Does Alzheimer’s Begin and Who Gets It?

    • Jack C. de la Torre
    Pages 1-20
  3. Storing and Keeping Memories

    • Jack C. de la Torre
    Pages 21-24
  4. Masquerading as Dementia

    • Jack C. de la Torre
    Pages 25-29
  5. Alzheimer’s Then and Now

    • Jack C. de la Torre
    Pages 31-38
  6. Unproven Hypotheses on the Cause of Alzheimer’s

    • Jack C. de la Torre
    Pages 39-48
  7. Alzheimer’s Noise

    • Jack C. de la Torre
    Pages 61-68
  8. The Social Contract and Alzheimer’s

    • Jack C. de la Torre
    Pages 69-73
  9. Genetics of Alzheimer’s Disease

    • Jack C. de la Torre
    Pages 75-83
  10. Powering the Brain

    • Jack C. de la Torre
    Pages 85-91
  11. Pharmaceuticals and Alzheimer’s

    • Jack C. de la Torre
    Pages 93-97
  12. Conditions That Can Promote Alzheimer’s

    • Jack C. de la Torre
    Pages 99-150
  13. The Good, the Bad, and the Ugly of Advanced Aging

    • Jack C. de la Torre
    Pages 151-168
  14. The Turning Point for Alzheimer’s

    • Jack C. de la Torre
    Pages 197-207
  15. Interventions that May Increase Cerebral Blood Flow

    • Jack C. de la Torre
    Pages 217-228
  16. Great Expectations

    • Jack C. de la Torre
    Pages 229-233

About this book

This compelling text provides an overview of the available technology for early detection and therapeutic management of vascular risk factors to Alzheimer’s before severe cognitive impairment symptoms appear. Chapters bring the reader from the trackless clinical research that has characterized Alzheimer’s progress for the last 20 years, to a nexus of new ideas and concepts that can change our outlook of this dementia. In-depth examinations of various hypotheses, preventive measures, current and prospective treatments are openly and clearly explored. The author discusses in depth his proposal of the vascular hypothesis of Alzheimer's disease which has become a mother-lode for basic and clinical studies and a key approach to the prevention of this dementia.Alzheimer’s Turning Point offers professionals, students and those looking to learn more about this disorder a fresh clinical perspective of this devastating disease.



Authors and Affiliations

  • University of Texas at Austin, Austin, USA

    Jack C. de la Torre

About the author

Jack C. de la Torre, MD, PhD

Professor of Neuropsychology (Adjunct)

Department of Psychology

University of Texas at Austin,

1 University Station

Austin, Texas



Dr. Jack de la Torre is a leading authority in the field of Alzheimer's disease (AD). In 1993, he first advanced the concept of AD as a vascular disorder with neurodegenerative consequences in a series of basic and clinical papers that culminated in the CATCH (critically-attained threshold of cerebral hypoperfusion) vascular hypothesis of AD. The vascular hypothesis of AD has had a profound impact and influence on research studies involving epidemiology, neuroimaging, neuropathology and therapeutics that continue to clarify the pathophysiology and pathogenesis of Alzheimer dementia. Dr. de la Torre has edited or co-edited 10 volumes on the subject of vascular factors in AD and published over 200 peer reviewed papers on neurodegeneration, neuropathology and neurotransmission. He has held professorial appointments in the Departments of Neurosurgery at the University of Chicago, Northwestern University, University of Ottawa, and in Pathology at Case Western Reserve University. Dr. de la Torre continues his active research on Alzheimers disease as an Adjunct Professor in the Department of Psychology at the University of Texas at Austin.   



Bibliographic Information

  • Book Title: Alzheimer’s Turning Point

  • Book Subtitle: A Vascular Approach to Clinical Prevention

  • Authors: Jack C. de la Torre

  • DOI: https://doi.org/10.1007/978-3-319-34057-9

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing Switzerland 2016

  • Hardcover ISBN: 978-3-319-34056-2Published: 08 July 2016

  • Softcover ISBN: 978-3-319-81667-8Published: 30 May 2018

  • eBook ISBN: 978-3-319-34057-9Published: 25 June 2016

  • Edition Number: 1

  • Number of Pages: XVI, 251

  • Number of Illustrations: 5 b/w illustrations, 29 illustrations in colour

  • Topics: Neurology, Psychiatry, Neurosciences

Buy it now

Buying options

eBook USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access