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Topics in Medicinal Chemistry

Heat Shock Protein Inhibitors

Success Stories

Editors: McAlpine, Shelli R., Edkins, Adrienne Lesley (Eds.)

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  • ISBN 978-3-319-32607-8
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About this book

Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.

Table of contents (8 chapters)

Table of contents (8 chapters)
  • Targeting the C-Terminus of Hsp90 as a Cancer Therapy

    Pages 1-20

    McConnell, Jeanette (et al.)

  • Hsp90 Co-chaperones as Drug Targets in Cancer: Current Perspectives

    Pages 21-54

    Edkins, Adrienne L.

  • Evaluating Dual Hsp90 and Hsp70 Inhibition as a Cancer Therapy

    Pages 55-80

    Buckton, Laura K. (et al.)

  • The Effect of Structure and Mechanism of the Hsp70 Chaperone on the Ability to Identify Chemical Modulators and Therapeutics

    Pages 81-129

    Manos-Turvey, Alexandra (et al.)

  • Allosteric Inhibitors of Hsp70: Drugging the Second Chaperone of Tumorigenesis

    Pages 131-162

    Srinivasan, Sharan R. (et al.)

Buy this book

eBook $229.00
price for USA in USD
  • ISBN 978-3-319-32607-8
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $299.99
price for USA in USD
  • ISBN 978-3-319-32605-4
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually ready to be dispatched within 3 to 5 business days.
Softcover $299.99
price for USA in USD
  • ISBN 978-3-319-81326-4
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually ready to be dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Heat Shock Protein Inhibitors
Book Subtitle
Success Stories
Editors
  • Shelli R. McAlpine
  • Adrienne Lesley Edkins
Series Title
Topics in Medicinal Chemistry
Series Volume
19
Copyright
2016
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing Switzerland
eBook ISBN
978-3-319-32607-8
DOI
10.1007/978-3-319-32607-8
Hardcover ISBN
978-3-319-32605-4
Softcover ISBN
978-3-319-81326-4
Series ISSN
1862-2461
Edition Number
1
Number of Pages
VII, 238
Topics

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