Editors:
- In depth insights into drug discovery and early drug development
- Latest technologies of target discovery and lead generation
- New approaches to transfer drug candidates to clinical development
Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 232)
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Table of contents (16 chapters)
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Front Matter
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Back Matter
About this book
This volume gives an overview of state of the art technologies and future developments in the field of preclinical pharmaceutical research. A balanced mix of experts from academia and industry give insight in selected new developments in the drug discovery pathway. The topics cover the different parts of the drug discovery process, starting with new developments in the target identification and validation area. The lead generation part as a next step focuses on the requirements and technologies to identify new small molecules as lead compounds for further optimization; in a second section the technologies to identify biologics as leads are addressed. The final part focuses on the pharmacological models and technologies to characterize new compounds and the impact of biomarkers to facilitate the transfer of drug candidates into the development phase.
Editors and Affiliations
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Drug Discovery-Cross Indication Platform, Bayer Pharma AG, Wuppertal, Germany
Ulrich Nielsch
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Drug Discovery-Cross Indication Platform, Bayer Pharma AG, Berlin, Germany
Ulrike Fuhrmann
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Drug Discovery-Global External Innovation & Alliances, Bayer Pharma AG, Berlin, Germany
Stefan Jaroch
About the editors
Prof. Dr. Stefan Jaroch, Bayer Pharma AG, Berlin, Germany
Bibliographic Information
Book Title: New Approaches to Drug Discovery
Editors: Ulrich Nielsch, Ulrike Fuhrmann, Stefan Jaroch
Series Title: Handbook of Experimental Pharmacology
DOI: https://doi.org/10.1007/978-3-319-28914-4
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing Switzerland 2016
Hardcover ISBN: 978-3-319-28912-0Published: 08 April 2016
Softcover ISBN: 978-3-319-80455-2Published: 25 April 2018
eBook ISBN: 978-3-319-28914-4Published: 30 March 2016
Series ISSN: 0171-2004
Series E-ISSN: 1865-0325
Edition Number: 1
Number of Pages: VIII, 341
Number of Illustrations: 37 b/w illustrations, 63 illustrations in colour
Topics: Pharmacology/Toxicology, Drug Safety and Pharmacovigilance, Medical Biochemistry, Metabolomics