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Applications of Mass Spectrometry in Microbiology

From Strain Characterization to Rapid Screening for Antibiotic Resistance

Editors: Demirev, Plamen, Sandrin, Todd R. (Eds.)

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  • Comprehensive treatment of mass spectrometry, a tool at the forefront of bioanalysis that continues to grow 
  • The applications have wide appeal, from practitioners to public health professionals  
  • Contributions from a broad range of authors, encompassing all aspects of the field, will lend the volume a balanced and encyclopedic perspective​  
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eBook $119.00
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  • ISBN 978-3-319-26070-9
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Hardcover $159.99
price for USA in USD
  • ISBN 978-3-319-26068-6
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  • Usually dispatched within 3 to 5 business days.
Softcover $159.99
price for USA in USD
  • ISBN 978-3-319-79888-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

In the last quarter century, advances in mass spectrometry (MS) have been at the forefront of efforts to map complex biological systems including the human metabolome, proteome, and microbiome. All of these developments have allowed MS to become a well-established molecular level technology for microorganism characterization. MS has demonstrated its considerable advantage as a rapid, accurate, and cost-effective method for microorganism identification, compared to conventional phenotypic techniques. In the last several years, applications of MS for microorganism characterization in research, clinical microbiology, counter-bioterrorism, food safety, and environmental monitoring have been documented in thousands of publications. Regulatory bodies in Europe, the US, and elsewhere have approved MS-based assays for infectious disease diagnostics. As of mid-2015, more than 3300 commercial MS systems for microorganism identification have been deployed worldwide in hospitals and clinical labs.

While previous work has covered broader approaches in using MS to characterize microorganisms at the species level or above, this book focuses on strain-level and subtyping applications. In twelve individual chapters, innovators, leaders and practitioners in the field from around the world have contributed to a comprehensive overview of current and next-generation approaches for MS-based microbial characterization at the subspecies and strain levels. Chapters include up-to-date reference lists as well as web-links to databases, recommended software, and other useful tools.

The emergence of new, antibiotic-resistant strains of human or animal pathogens is of extraordinary concern not only to the scientific and medical communities, but to the general public as well. Developments of novel MS-based assays for rapid identification of strains of antibiotic-resistant microorganisms are reviewed in the book as well. Microbiologists, bioanalytical scientists, infectious disease specialists, clinical laboratory and public health practitioners as well as researchers in universities, hospitals, government labs, and the pharmaceutical and biotechnology industries will find this book to be a timely and valuable resource. 

About the authors

Plamen A. Demirev, Johns Hopkins University Applied Physics Laboratory
Todd Sandrin, School of Mathematical and Natural Sciences, Arizona State University

Table of contents (13 chapters)

Table of contents (13 chapters)
  • Introduction

    Pages 1-10

    Demirev, Plamen (et al.)

  • Methods and Instrumentation in Mass Spectrometry for the Differentiation of Closely Related Microorganisms

    Pages 13-50

    Basile, Franco, PhD (et al.)

  • Sample Preparation Methods for the Rapid MS Analysis of Microorganisms

    Pages 51-71

    Devi, C. Shobha (et al.)

  • Advantages Offered by Proteomic Strategies for Rapid Biodetection

    Pages 73-81

    Fenselau, Catherine

  • Bottom-Up Proteomics Methods for Strain-Level Typing and Identification of Bacteria

    Pages 83-146

    Dworzanski, Jacek P., Ph.D.

Buy this book

eBook $119.00
price for USA in USD (gross)
  • ISBN 978-3-319-26070-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $159.99
price for USA in USD
  • ISBN 978-3-319-26068-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $159.99
price for USA in USD
  • ISBN 978-3-319-79888-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Applications of Mass Spectrometry in Microbiology
Book Subtitle
From Strain Characterization to Rapid Screening for Antibiotic Resistance
Editors
  • Plamen Demirev
  • Todd R. Sandrin
Copyright
2016
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing Switzerland
eBook ISBN
978-3-319-26070-9
DOI
10.1007/978-3-319-26070-9
Hardcover ISBN
978-3-319-26068-6
Softcover ISBN
978-3-319-79888-2
Edition Number
1
Number of Pages
VIII, 336
Number of Illustrations
36 b/w illustrations, 32 illustrations in colour
Topics