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The Discreet Charm of Protein Binding Sites

Authors: Yariv, Joseph

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  • Covers the great discoveries of protein crystallography of the 20th century, as told by one of the protagonists
  • Explains the unique selectivity of proteins in the binding of small molecules
  • Addresses the most important questions about protein binding sites
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eBook $99.00
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  • ISBN 978-3-319-24996-4
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Hardcover $129.00
price for USA in USD
  • ISBN 978-3-319-24994-0
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
Softcover $129.00
price for USA in USD
  • ISBN 978-3-319-79717-5
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
About this book

This book is a passionate account of the scientific breakthroughs that led to the solution of the first protein structures and to the understanding of their function at atomic resolution. The book is divided into self-standing chapters that each deal with a protein or protein family. The subject is presented in a fluid, non-technical style that will engage student and scientists in biochemistry, biophysics, molecular and structure biology and physiology.

About the authors

Joseph Yariv graduated from The Hebrew University in Jerusalem with a Ph.D. in biochemistry. After postdoctoral studies  at the Sloan Kettering Institute and Columbia University in  New York, USA  he joined the department of biophysics of The Weizmann Institute of Science in Rehovot, Israel where he worked until his retirement in  the position of Senior Scientist. His work dealt with protein isolation, crystallization and structure solution. He was the first to label a methionine  in the active-site of b-galacosidase of E. coli. He produced crystals of concanavalin A  complexes  with methyl-glucoside and with methyl-mannoside  and  participated in solving the structure  of this protein binding-site for saccharides. He collaborated with physicists at The Hebrew University in Jerusalem in studying by Mossbauer Spectroscopy the state of iron in E. coli that led to the isolation of bacterioferritin, the first ferritin-like molecule to be found in bacteria and named as such, and solution of its structure.  

Reviews

“This study is quite probably the inspiration behind ‘The discreet charm’, which is a personal, and passionate story of how proteins interact with other chemical moieties, be it organic molecules or other proteins. … The book is well illustrated, both with copies of original figures from the referenced bibliography, as well as schematic structure figures prepared using Protein Data Bank (PDB) entries. … the book is a pleasure to read.” (Zygmunt Derewenda, Crystallography Reviews, May, 2016)


“Many thanks for your beautifully illustrated and readable book on protein binding sites. Good choice of examples and good coverage.” (Pauline Harrison, The University of Sheffield, Department of Molecular Biology and Biotechnology, UK) 

Table of contents (5 chapters)

Table of contents (5 chapters)

Buy this book

eBook $99.00
price for USA in USD
  • ISBN 978-3-319-24996-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $129.00
price for USA in USD
  • ISBN 978-3-319-24994-0
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
Softcover $129.00
price for USA in USD
  • ISBN 978-3-319-79717-5
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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Bibliographic Information

Bibliographic Information
Book Title
The Discreet Charm of Protein Binding Sites
Authors
Copyright
2016
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing Switzerland
eBook ISBN
978-3-319-24996-4
DOI
10.1007/978-3-319-24996-4
Hardcover ISBN
978-3-319-24994-0
Softcover ISBN
978-3-319-79717-5
Edition Number
1
Number of Pages
XIII, 60
Number of Illustrations
6 b/w illustrations, 10 illustrations in colour
Topics