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Advances in Experimental Medicine and Biology

Lung Cancer and Personalized Medicine: Novel Therapies and Clinical Management

Editors: Ahmad, Aamir, Gadgeel, Shirish M. (Eds.)

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  • Provides a better understanding of lung cancer, the factors that make it lethal, and current research focused on developing personalized treatment plans
  • Addresses statistics and epidemiology of lung cancer, along with the incidence of lung cancer in non-smokers
  • Evaluates the state of current therapies–immune, targeted therapies against EGFR TKIs, KRAS, ALK and the associated challenges, especially resistance mechanisms
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  • ISBN 978-3-319-24932-2
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Softcover $179.99
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About this book

This, the second of two volumes on personalized medicine in lung cancer, touches upon the recent progress in targeted drug development based on genomics; emerging biomarkers and therapeutic targets such as EMT, cancer stem cells, and the tumor microenvironment; current personalized clinical management and radiation therapy for lung cancers; and the promise of epigenetics and next-generation sequencing for the advancements towards personalized therapy of lung cancer patients. With chapters on state-of-the-art therapies and technologies written by leading experts working to develop novel companion diagnosis tools for the personalized treatment of lung cancer patients, this volume brings readers up-to-date by presenting the current knowledge on the efforts to make personalized management of lung cancer patients a reality. 

About the authors

Aamir Ahmad, PhD, is a Scientist at the Wayne State University School of Medicine Department of Pathology and the Karmanos Cancer Institute, with over 100 published scientific articles in peer-reviewed journals and many book chapters. He has been a member of leading cancer organizations such as American Association for Cancer Research (AACR, Philadelphia, USA) and International Union against Cancer (UICC, Geneva, Switzerland). In addition to serving as a reviewer for a number of peer-reviewed scientific journals, he is currently a Section Editor for the journal PLoS ONE responsible for policy drafts for the journal and identification and management of special issues. In addition to the current volume, Dr. Ahmad has worked with Springer to edit two more volumes, Breast Cancer Metastasis and Drug Resistance and Lung Cancer and Personalized Medicine: Current Knowledge and Therapies.

Shirish M. Gadgeel is a Professor in the Department of Oncology at Karmanos Cancer Institute/Wayne State University in Detroit. He is also the co-leader of the Molecular Therapeutics Program of Karmanos Cancer Institute and the Leader of the Multidisciplinary Thoracic Oncology team. He is

a member of several professional societies, including the American Society of Clinical Oncology and the International Association for the Study of Lung Cancer. He currently serves on the Editorial Board of the journals Cancer and Clinical Lung Cancer. Dr. Gadgeel has been and is a Principal Investigator of several trials focused on the treatment of Lung Cancer. He has over 80 peer reviewed publications.  

Table of contents (11 chapters)

Table of contents (11 chapters)
  • Lung Cancer Genomics in the Era of Accelerated Targeted Drug Development

    Pages 1-23

    Wijesinghe, Priyanga, Ph.D. (et al.)

  • Emerging Biomarkers in Personalized Therapy of Lung Cancer

    Pages 25-36

    Cagle, Philip T., M.D. (et al.)

  • Epithelial Mesenchymal Transition in Aggressive Lung Cancers

    Pages 37-56

    Mittal, Vivek

  • The Role of Cancer Stem Cells in Recurrent and Drug-Resistant Lung Cancer

    Pages 57-74

    Suresh, Raagini (et al.)

  • The Microenvironment of Lung Cancer and Therapeutic Implications

    Pages 75-110

    Mittal, Vivek (et al.)

Buy this book

eBook $139.00
price for USA in USD
  • ISBN 978-3-319-24932-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-3-319-24931-5
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
Softcover $179.99
price for USA in USD
  • ISBN 978-3-319-79702-1
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Lung Cancer and Personalized Medicine: Novel Therapies and Clinical Management
Editors
  • Aamir Ahmad
  • Shirish M. Gadgeel
Series Title
Advances in Experimental Medicine and Biology
Series Volume
890
Copyright
2016
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing Switzerland
eBook ISBN
978-3-319-24932-2
DOI
10.1007/978-3-319-24932-2
Hardcover ISBN
978-3-319-24931-5
Softcover ISBN
978-3-319-79702-1
Series ISSN
0065-2598
Edition Number
1
Number of Pages
X, 231
Number of Illustrations
1 b/w illustrations, 21 illustrations in colour
Topics

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