The Development of Immunologic Competence

Authors: Ribatti, Domenico

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  • Builds understanding of the immune system and its evolution
  • Provides a theoretical grounding in immunologic competence, for immunology and neurobiology
  • Improves epistemological awareness of disciplinary problems through the history of immunology
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eBook $129.00
price for USA in USD (gross)
  • ISBN 978-3-319-24663-5
  • Digitally watermarked, DRM-free
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Hardcover $169.99
price for USA in USD
  • ISBN 978-3-319-24661-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $169.99
price for USA in USD
  • ISBN 978-3-319-79655-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book traces significant aspects of the history of immunology, exploring the immune system and immunodeficiency. The author recounts human hematopoietic development, and how a distinction of the immune system into thymus-dependent and thymus-independent components has been demonstrated in different animal species, including amphibians, birds, and mammals.

Other themes explored in this book include discoveries about the role of the thymus of the Bursa of Fabricius in the development of immunologic competence, and observations on the changes in the lymphoid organs after bursectomy and thymectomy in chickens. Readers will discover how the bursa provides a unique microenvironment for the proliferation and differentiation of B cells, while thymectomized and irradiated animals were deficient in lymphocytes that mediated inflammatory responses, as assessed by skin graft rejection, delayed-type hypersensitivity, and graft versus host reaction.

A clear perspective for understanding several diseases and also the entire lymphoid system emerges through the experiments and extensive histopathological studies of patients with primary immunodeficiency diseases that are described in these chapters.

Researchers in the life sciences, in biomedicine and the history of medicine will all find something of value in this highly engaging work. It will also appeal to those with an interest in public health and neurobiology.

Table of contents (5 chapters)

Table of contents (5 chapters)

Buy this book

eBook $129.00
price for USA in USD (gross)
  • ISBN 978-3-319-24663-5
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
  • ISBN 978-3-319-24661-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $169.99
price for USA in USD
  • ISBN 978-3-319-79655-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
The Development of Immunologic Competence
Authors
Copyright
2015
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing Switzerland
eBook ISBN
978-3-319-24663-5
DOI
10.1007/978-3-319-24663-5
Hardcover ISBN
978-3-319-24661-1
Softcover ISBN
978-3-319-79655-0
Edition Number
1
Number of Pages
VIII, 60
Number of Illustrations
7 b/w illustrations, 22 illustrations in colour
Topics