Essentials of Cerebellum and Cerebellar Disorders

1. Front Matter

   Pages i-x

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2. Introduction

   • Donna L. Gruol, Noriyuki Koibuchi, Mario Manto, Marco Molinari, Jeremy D. Schmahmann, Ying Shen

   Pages 1-2

3. Brief Historical Note

   1. Front Matter

      Pages 3-3

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   2. A Brief History of the Cerebellum

      • Jeremy D. Schmahmann

      Pages 5-20

   3. Pivotal Insights: The Contributions of Gordon Holmes (1876–1965) and Olof Larsell (1886–1964) to Our Understanding of Cerebellar Function and Structure

      • Duane E. Haines

      Pages 21-29

4. Anatomy and Histology of the Cerebellum

   1. Front Matter

      Pages 31-31

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   2. Gross Anatomy of the Cerebellum

      • Jan Voogd, Enrico Marani

      Pages 33-38

   3. Vascular Supply and Territories of the Cerebellum

      • Qiaoshu Wang, Louis R. Caplan

      Pages 39-54

   4. The Olivocerebellar Tract

      • Yuanjun Luo, Izumi Sugihara

      Pages 55-61

   5. Precerebellar Nuclei

      • Mayumi Yamada, Mikio Hoshino

      Pages 63-67

   6. Vestibular Nuclei and Their Cerebellar Connections

      • Neal H. Barmack

      Pages 69-78

   7. Spinocerebellar and Cerebellospinal Pathways

      • Tom J. H. Ruigrok

      Pages 79-88

   8. Visual Circuits

      • Manuel Jan Roth, Axel Lindner, Peter Thier

      Pages 89-100

   9. The Cerebrocerebellar System

      • Jeremy D. Schmahmann

      Pages 101-115

   10. Cerebello-Cerebral Feedback Projections

       • Kim van Dun, Mario Manto, Peter Mariën

       Pages 117-123

5. Embryology and Development of the Cerebellum

   1. Front Matter

      Pages 125-125

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   2. Cerebellar Neurogenesis

      • Ketty Leto, Richard Hawkes, G. Giacomo Consalez

      Pages 127-135

   3. Zones and Stripes

      • Carol Armstrong, Richard Hawkes

      Pages 137-141

   4. Specification of Cerebellar Neurons

      • Mikio Hoshino

      Pages 143-147

   5. Cerebellar Nucleus Development

      • Hong-Ting Prekop, Richard J. T. Wingate

      Pages 149-154

Essentials of the Cerebellum and Cerebellar Disorders is the first book of its kind written specifically for graduate students and clinicians. It is based on the 4-volume treatise, Handbook of the Cerebellum and Cerebellar Disorders (Springer, 2013), the definitive reference for scientists and neurologists in the field of cerebellar neurobiology. There have been fundamental advances in the basic science and clinical neurology of the cerebellum and its role in sensorimotor function and cognition. This monograph makes this large and expanding body of knowledge readily accessible to trainees and clinicians alike. The editors are world leaders in the field, and the chapters are authored by an international panel of experts drawn from ataxia clinics and cerebellar laboratories throughout North America, Europe and Asia. Essentials provides a solid grounding in the field of cerebellar research and ataxiology from cerebellar circuity to clinical practice, and it serves as a springboard to a deeper appreciation of both the principles and the complexities of cerebellar neurobiology. Clinicians are expected to have a deep appreciation of cerebellar disorders, not only in specialized ataxia clinics but also in adult and pediatric neurology, neurosurgery, psychiatry and neuropsychology practices, and in outpatient and inpatient rehabilitation settings. This book is an indispensable resource for students and practitioners navigating the evolving field of cerebellar motor and cognitive neurology. It also links to the more expansive Handbook for those who need to explore the topics in this monograph in greater depth.

• Cerebellum
• Ataxias
• Brain
• Cerebellar cortex
• Cerebellar nuclei

• Molecular and Cellular Neuroscience Department, The Scripps Research Institute, La Jolla, USA

  Donna L. Gruol

• Department of Integrative Physiology, Gunma University Graduate School of Medicine, Maebashi, Japan

  Noriyuki Koibuchi

• FNRS, ULB-Erasme, Bruxelles, Belgium

  Mario Manto

• Clinical Translational Research, Santa Lucia Foundation, Rome, Italy

  Marco Molinari

• Ataxia Unit, Cognitive Behavioral Neurology Unit, Laboratory for Neuroanatomy and Cerebellar Neurobiology, Department of Neurology Massachusetts General Hospital, Harvard Medical School, Boston, USA

  Jeremy D. Schmahmann

• Department of Neurobiology, Zhejiang University School of Medicine, Hangzhou, China

  Ying Shen

International panel of editors: the 6 editors have a strong experience in research and/or in the clinic. They all devote most of their time to cerebellar research and have regular teaching duties for several of them. Through their networks, their students and the attendance to international conferences, they will contribute to a fast dissemination of the book.

International panel of authors: the book will gather an international panel of scientists who are key-players in the field. They are located in USA, in Europe and in Asia. Many of them have contributed to the Handbook and we also aim to attract novel authors or young talented scientists. The authors will come from the best clinical centers, universities or research centers in the world.

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