Overview
- Covers applications of surface-enhanced Raman scattering technique in the life sciences
- Presents the instrumentations of SERS for bioanalytical studies and sensing
- The didactic, comprehensible approach and the many illustrative figures makes the book accessible to students as well
- Includes supplementary material: sn.pub/extras
Part of the book series: Biological and Medical Physics, Biomedical Engineering (BIOMEDICAL)
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Table of contents (8 chapters)
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Front Matter
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Back Matter
Keywords
About this book
This book gives an overview of recent developments in RS and SERS for sensing and biosensing considering also limitations, possibilities and prospects of this technique. Raman scattering (RS) is a widely used vibrational technique providing highly specific molecular spectral patterns. A severe limitation for the application of this spectroscopic technique lies in the low cross section of RS. Surface-enhanced Raman scattering (SERS) spectroscopy overcomes this problem by 6-11 orders of magnitude enhancement compared with the standard RS for molecules in the close vicinity of certain rough metal surfaces. Thus, SERS combines molecular fingerprint specificity with potential single-molecule sensitivity. Due to the recent development of new SERS-active substrates, labeling and derivatization chemistry as well as new instrumentations, SERS became a very promising tool for many varied applications, including bioanalytical studies and sensing. Both intrinsic and extrinsic SERS biosensing schemes have been employed to detect and identify small molecules, nucleic acids and proteins, and also for cellular and in vivo sensing.
Authors and Affiliations
Bibliographic Information
Book Title: Surface-Enhanced Raman Spectroscopy
Book Subtitle: Bioanalytical, Biomolecular and Medical Applications
Authors: Marek Prochazka
Series Title: Biological and Medical Physics, Biomedical Engineering
DOI: https://doi.org/10.1007/978-3-319-23992-7
Publisher: Springer Cham
eBook Packages: Physics and Astronomy, Physics and Astronomy (R0)
Copyright Information: Springer International Publishing Switzerland 2016
Hardcover ISBN: 978-3-319-23990-3Published: 18 December 2015
Softcover ISBN: 978-3-319-79565-2Published: 30 March 2019
eBook ISBN: 978-3-319-23992-7Published: 12 December 2015
Series ISSN: 1618-7210
Series E-ISSN: 2197-5647
Edition Number: 1
Number of Pages: XVI, 221
Number of Illustrations: 51 b/w illustrations, 27 illustrations in colour
Topics: Biological and Medical Physics, Biophysics, Biological Techniques, Spectroscopy and Microscopy, Measurement Science and Instrumentation, Medical and Radiation Physics