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Current Topics in Microbiology and Immunology

Long Non-coding RNAs in Human Disease

Editors: Morris, Kevin V. (Ed.)

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  • Summarizes the tremendous progress made within the last decade in understanding the roles of lncRNA in human disease
  • Bridges the divide between inferring lncRNA mechanisms and targeting lncRNAs by means of rational therapeutics
  • Stresses the vital role of lncRNA disease mechanisms for a necessary and profound reassessment of Genome-Wide Association studies in the new era of personalized medicine
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eBook $129.00
price for USA in USD (gross)
  • ISBN 978-3-319-23907-1
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Hardcover $169.99
price for USA in USD
  • ISBN 978-3-319-23906-4
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  • Usually dispatched within 3 to 5 business days.
Softcover $169.99
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  • ISBN 978-3-319-79551-5
  • Free shipping for individuals worldwide
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About this book

This volume focuses on the roles of long non-coding RNAs (lncRNAs) in contexts ranging from human cancers to cardiovascular disease and ageing. The role of lncRNAs in X-inactivation and those lncRNAs derived from pseudogenes, past retroelements integrated within the human genome, as well as the role these pseudogene-derived lncRNAs play in cancer development are discussed in detail. Further, the book examines the function of lncRNAs in diseases such as diabetes, in smooth muscle formation, and in the modulation of nuclear receptors, as well as in connection with perspectives on the development of personalized therapeutics. It offers an appealing and insightful resource for scientists and clinicians alike.

About the authors

Kevin Morris is an Associate Professor at the Department of Molecular and Experimental Medicine, The Scripps Research Institute in La Jolla, CA, USA. The responsible series editor is Peter K. Vogt, The Scripps Research Institute in La Jolla, CA, USA.

Table of contents (10 chapters)

Table of contents (10 chapters)
  • Understanding the Complex Circuitry of lncRNAs at the X-inactivation Center and Its Implications in Disease Conditions

    Pages 1-27

    Charles Richard, John Lalith (et al.)

  • Long Non-coding RNA ANRIL and Polycomb in Human Cancers and Cardiovascular Disease

    Pages 29-39

    Aguilo, Francesca (et al.)

  • Form and Function of Exosome-Associated Long Non-coding RNAs in Cancer

    Pages 41-56

    Hewson, Chris (et al.)

  • Long Noncoding RNAs in Lung Cancer

    Pages 57-110

    Roth, Anna (et al.)

  • Pseudogene-Expressed RNAs: Emerging Roles in Gene Regulation and Disease

    Pages 111-126

    Grandér, Dan (et al.)

Buy this book

eBook $129.00
price for USA in USD (gross)
  • ISBN 978-3-319-23907-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
  • ISBN 978-3-319-23906-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $169.99
price for USA in USD
  • ISBN 978-3-319-79551-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Long Non-coding RNAs in Human Disease
Editors
  • Kevin V. Morris
Series Title
Current Topics in Microbiology and Immunology
Series Volume
394
Copyright
2016
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing Switzerland
eBook ISBN
978-3-319-23907-1
DOI
10.1007/978-3-319-23907-1
Hardcover ISBN
978-3-319-23906-4
Softcover ISBN
978-3-319-79551-5
Series ISSN
0070-217X
Edition Number
1
Number of Pages
VIII, 262
Topics