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  • Conference proceedings
  • © 2015

Physical Biology of Proteins and Peptides

Theory, Experiment, and Simulation

  • Top researchers in the field of theory, simulation and experiment of proteins and peptides contribute their findings

  • Reaches a wide audience from biologists, biochemists, organic chemists and engineers to computational scientists, physicists and mathematicians

  • Explores induce-fit docking in computer-aided drug development

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Table of contents (10 papers)

  1. Front Matter

    Pages i-xi
  2. The Structural Determinants of the Immunoglobulin Light Chain Amyloid Aggregation

    • Luis Del Pozo-Yauner, Baltazar Becerril, Adrián Ochoa-Leyva, Sandra Leticia Rodríguez-Ambriz, Julio Isael Pérez Carrión, Guadalupe Zavala-Padilla et al.
    Pages 1-28
  3. Determination of the Size of the Primary and Secondary Folding Nuclei of Protofibrils from the Concentration Dependence of the Rate and the Lag-Time of Their Formation

    • Alexey V. Finkelstein, Nikita V. Dovidchenko, Olga M. Selivanova, Maria Yu. Suvorina, Alexey K. Surin, Oxana V. Galzitskaya
    Pages 47-66
  4. Modulation of Cholera Toxin Structure/Function by Hsp90

    • Michael Taylor, Christopher B. T. Britt, Jennifer Fundora, Ken Teter
    Pages 67-79
  5. Function, Structure and Stability of Human Gamma D Crystallins: A Review

    • Lina Rivillas-Acevedo, Arline Fernández-Silva, Carlos Amero
    Pages 81-98
  6. Multi-scale Approaches to Dynamical Transmission of Protein Allostery

    • Philip D. Townsend, Thomas L. Rodgers, Ehmke Pohl, Mark R. Wilson, Martin J. Cann, Tom C. B. McLeish
    Pages 141-152
  7. Dynamics of Membrane Proteins and Lipid Bilayers

    • Héctor Eduardo Jardón-Valadez
    Pages 153-159
  8. What Makes a Transcriptional Master Regulator? A Systems Biology Approach

    • Enrique Hernández-Lemus, Karol Baca-López, Hugo Tovar
    Pages 161-174
  9. Back Matter

    Pages 175-177

About this book

This book covers the latest developments in the physical biology of proteins and peptides. Key insights into microscopic and macroscopic approaches to describe biologically relevant macromolecules and their interactions are provided. This book also covers a wide range of tools, including theoretical methods as statistical mechanics, normal mode analysis, kinetic theory and stochastic processes, and all-atom and coarse-grained molecular dynamics simulations. New experimental techniques are also discussed, particularly related to amiloidogenic peptides and their mutations. This is an excellent book for molecular biologists, physicists, computational scientists, and chemists. It covers cutting-edge research in this exciting, interdisciplinary research field.

This book also:

Discusses the latest developments in the physical biology of proteins, peptides and enzymes covering theoretical, computational, and experimental approaches

Broadens readers’ understanding on the r

ole of intra- and inter-molecular interactions as a fundamental cornerstone of macroscopic biological properties of macromolecules

Provides a wide and useful perspective on different aspects of the physics, biology, and chemistry of proteins and peptides suitable for interdisciplinary research.

Editors and Affiliations

  • Autonomous University of Mexico City, Mexico City, Mexico

    Luis Olivares-Quiroz

  • (Iztapalapa), Autonomous Metropolitan University, Mexico City, Mexico

    Orlando Guzmán-López

  • (Lerma), Lerma de Villada, Autonomous Metropolitan University, Mexico City, Mexico

    Hector Eduardo Jardón-Valadez

Bibliographic Information

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access