Bioactive Sphingolipids in Cancer Biology and Therapy

Editors: Hannun, Y.A., Luberto, C., Mao, C., Obeid, L.M. (Eds.)

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  • Examines the roles and functions of sphingolipids in the development, progression and treatment of various cancers
  • Explores the use of innovative approaches for quantitative analysis and imaging which could have the potential benefit of helping to develop novel cancer therapeutics
  • Appeals to researchers in the fields of cancer and lipid metabolism/signaling
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eBook $129.00
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  • ISBN 978-3-319-20750-6
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Hardcover $219.99
price for USA in USD
  • ISBN 978-3-319-20749-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $169.99
price for USA in USD
  • ISBN 978-3-319-35371-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This volume presents information on both the basic and clinical aspects of sphingolipid-metabolizing enzymes in various cancers. The volume also includes discussions of the innovative techniques and approaches for quantitative analysis and imaging that could significantly impact the general understanding of this topic, and the potential benefit of targeting sphingolipid enzymes to develop novel cancer therapeutics. As well, the volume includes a critical examination of the specific pathways and pathobiologies associated with the altered regulation of sphingolipid metabolism as a contributor to the development and/or maintenance of pathological conditions such as cancer.

About the authors

Yusuf A. Hannun, MD, is Director, Stony Brook Cancer Center, Vice Dean, Cancer Medicine, and Professor, Biochemistry and Cell Biology, Stony Brook University. He is a renowned molecular biologist and physician-scientist investigating the molecular mechanisms of cancer, with an expertise in sphingolipids. Dr. Hannun is currently on the Editorial Board of several journals, including Biomedicine and Biotechnology, Frontiers in Membrane Physiology, and Biophysics, Chemistry and Physics of Lipids, and has received several honors, including the ASBMB Avanti Award in Lipids and ISI Highly Citied Researchers (in Biology and Biochemistry), and is Fellow, the American Association and Advancement of Science. He has published 448 scientific papers, which have received more than 34,100 citations.

 

Chiara Luberto, Ph.D., is Research Associate Professor of Physiology and Biophysics, Stony Brook University.

 

Cungui Mao, Ph.D., is Associate Professor of Medicine, Stony Brook University.

 

Lina Marie Obeid, M.D., is Professor of Medicine and Dean of Research, Stony Brook University.

Table of contents (21 chapters)

Table of contents (21 chapters)
  • Basics of Sphingolipid Metabolism and Signalling

    Pages 1-20

    Colacios, Céline (et al.)

  • Role of Sphingolipids in Hematological Malignancies: Lymphoproliferative Disorders

    Pages 23-51

    Sawai, Hirofumi (et al.)

  • Role of Sphingolipids in Hematological Malignancies: Myeloproliferative Disorders

    Pages 53-79

    Moorthi, Sitapriya (et al.)

  • Sphingolipids as Mediators of Breast Cancer Progression, Metastasis, Response and Resistance to Chemotherapy

    Pages 81-106

    Newcomb, Benjamin (et al.)

  • Role of Sphingolipids in Non-melanoma Skin Cancer

    Pages 107-122

    Lin, Chih-Li (et al.)

Buy this book

eBook $129.00
price for USA in USD (gross)
  • ISBN 978-3-319-20750-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-3-319-20749-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $169.99
price for USA in USD
  • ISBN 978-3-319-35371-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Bioactive Sphingolipids in Cancer Biology and Therapy
Editors
  • Yusuf A. Hannun
  • Chiara Luberto
  • Cungui Mao
  • Lina Marie Obeid
Copyright
2015
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing Switzerland
eBook ISBN
978-3-319-20750-6
DOI
10.1007/978-3-319-20750-6
Hardcover ISBN
978-3-319-20749-0
Softcover ISBN
978-3-319-35371-5
Edition Number
1
Number of Pages
XI, 490
Number of Illustrations
19 b/w illustrations, 68 illustrations in colour
Topics